ABOUT ROCHE CUSTOMBIOTECH
As part of Roche, CustomBiotech has been a leader in supplying innovative, high-quality products to forward-thinking biopharma and diagnostics businesses for more than 50 years. Our pioneering biopharma and diagnostic experts work together at one of Europe’s largest and most productive biotechnology centers. This is where Roche continually creates a wide range of drugs and diagnostics, including critical raw materials, ingredients, quality control kits and in-process analyzers.
In the fast-paced, volatile healthcare industry, you must stay ahead of your competition while continuing to raise the standards of care.
Roche CustomBiotech is a reliable partner who:
- Invests in the innovations and quality assurance that can elevate your biopharma and diagnostic business
- Offers a secure and compliant global supply chain
- Can co-create solutions to the specific needs of your business
Our high-quality raw materials and reliable service will help you grow your business and deliver better healthcare products.
VIDEOS
Future-Proof Your Bioprocess: The Science And Supply Chain Of Roche Enzymes
High-purity trypsin and carboxypeptidase B enable critical protein processing in biopharma manufacturing. Learn how animal-free, GMP-grade production meets exacting quality standards for growing operations.
Uncoupling Yield And Glycosylation In Downstream Processing
This video explores how in vitro glycoengineering uncouples glycosylation from fermentation variables, removing production compromises to safely optimize therapeutic protein yield and quality.
Uncoupling Protein Yield From Glycosylation Optimization
Watch a step-by-step breakdown of cell-free enzymatic reactions using glycosyltransferases to achieve high glycan homogeneity on N-linked backbones like G0 and G0F structures.
Unlock Your Manufacturing Potential With Scalable Glycoengineering
Achieve precise, optimal glycan structures without sacrificing vital protein output. Explore a scalable technique to improve therapeutic quality and significantly shorten your production timelines.
CONTACT INFORMATION
Roche CustomBiotech
Sandhofer Straße 116
Mannheim, 68305
GERMANY
FEATURED INSIGHTS
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![GettyImages-1227180008 facility design, lab]( "De-Risking Glycosylation: Scaling In Vitro Glycoengineering From Lab To GMP")
Access a phased, risk-minimized integration framework to scale your enzymatic post-production process seamlessly from initial lab-scale feasibility up to commercial GMP readiness.
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![GettyImages-1033017918 cell membrane]( "Tuning Glycans For High Efficacy In Next-Gen Biologics")
Discover how precise downstream glycan engineering addresses biopharma pain points, extending therapeutic half-life and ensuring absolute analytical similarity for biosimilars.
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![GettyImages-2240372856 antibody, glycan]( "From Black Box To Precision: A New Era Of Glycan Control")
Shift from unpredictable cell-line engineering to an enzymatic post-production step. Learn how this paradigm shift eliminates biological variability to ensure optimal drug performance.
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![GettyImages-181689527 cell culture]( "Proven Efficiency: Optimizing Cell Detachment With Recombinant GMP Trypsin")
Recombinant trypsin at optimized concentrations delivers effective cell detachment with reduced damage risk. Animal-free and GMP-compliant, it maintains high viability across multiple cell lines.
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![GettyImages-1405590436 pharma equipment]( "A Practical Framework For Scaling Post-Fermentation In Vitro Glycoengineering")
Evaluate the technical suitability and implementation of simultaneous galactosylation and sialylation across early downstream intermediates to streamline routine manufacturing.
SOLUTIONS
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![Roche - mycoplasma]( "What Activity Assays Miss: Detecting Inactive Trypsin Fragments In Final Formulation")
High-sensitivity immunoassays detect active and inactive enzyme residues at 0.5 ng/ml, addressing quality control gaps where activity-based methods fail to identify immunogenic protein fragments.
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![Roche -trypsin]( "Optimize Your Downstream Yield: The Purity Advantage Of Rec. GMP Trypsin")
Recombinant trypsin provides consistent β-trypsin ratios and animal-component-free production, reducing costs while improving biopharmaceutical manufacturing yield through self-catalytic activation.
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![Roche - FcRn]( "Mastering PK Control: Enhancing Pharmacokinetic Predictability With FcRn Affinity Tools")
Standardized affinity chromatography evaluates IgG-FcRn binding across pH gradients, revealing how structural variants and modifications impact antibody half-life for quality control applications.
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![Roche - proteases]( "The Pichia Advantage: Avoiding Endotoxin Risks In Recombinant CpB Sourcing")
Removing animal-derived materials from biopharma manufacturing doesn't have to mean compromising on enzyme performance, consistency, or regulatory readiness in critical production workflows.
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![Roche - IVGE]( "What If You Could Engineer Glycans After Purification?")
Variations in glycosylation can impact your therapeutic protein's safety and efficacy. Take control of this critical quality attribute with in vitro glycoengineering for predictable outcomes.
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![Roche - glycolysation brochure]( "The Glycoengineering Toolbox: Matched GMP Enzymes And Sugars")
Explore a complete toolbox of highly active, animal-origin-free glycosyltransferases and activated sugars scalable from milligram to kilogram quantities for flexible bioprocessing.
