ABOUT ROCHE CUSTOMBIOTECH
As part of Roche, CustomBiotech has been a leader in supplying innovative, high-quality products to forward-thinking biopharma and diagnostics businesses for more than 50 years. Our pioneering biopharma and diagnostic experts work together at one of Europe’s largest and most productive biotechnology centers. This is where Roche continually creates a wide range of drugs and diagnostics, including critical raw materials, ingredients, quality control kits and in-process analyzers.
In the fast-paced, volatile healthcare industry, you must stay ahead of your competition while continuing to raise the standards of care.
Roche CustomBiotech is a reliable partner who:
- Invests in the innovations and quality assurance that can elevate your biopharma and diagnostic business
- Offers a secure and compliant global supply chain
- Can co-create solutions to the specific needs of your business
Our high-quality raw materials and reliable service will help you grow your business and deliver better healthcare products.
VIDEOS
Future-Proof Your Bioprocess: The Science And Supply Chain Of Roche Enzymes
High-purity trypsin and carboxypeptidase B enable critical protein processing in biopharma manufacturing. Learn how animal-free, GMP-grade production meets exacting quality standards for growing operations.
Find The Perfect Balance Between Yield And Desired Glycosylation
Achieving desired glycosylation for therapeutic proteins can be difficult. Explore innovative approaches to optimize this critical quality attribute.
Stop Compromising Between Yield And Glycosylation Quality
Optimize your therapeutic protein's glycan profile. Learn about a straightforward, enzymatic approach to gain greater control over this critical quality attribute.
Unlock Your Manufacturing Potential With Scalable Glycoengineering
Achieve precise, optimal glycan structures without sacrificing vital protein output. Explore a scalable technique to improve therapeutic quality and significantly shorten your production timelines.
CONTACT INFORMATION
Roche CustomBiotech
Sandhofer Straße 116
Mannheim, 68305
GERMANY
FEATURED INSIGHTS
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![Multi pipette, sample preparation, bioassay, in vitro cell-GettyImages-2058885436]( "A Comprehensive Blueprint For In Vitro Glycoengineering Adoption")
In vitro glycoengineering enables precise control of therapeutic protein glycosylation, streamlining product consistency and development through a phased, risk-managed integration after initial purification.
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![Getty Images-823447656-vector-viral-lab-AAV-cell-development]( "Beyond Glycan Control: The IVGE Advantage In Key Biopharma Applications")
In Vitro Glycoengineering (IVGE) precisely controls glycosylation to optimize biopharma workflows, serving as a critical platform for advancing key therapeutic areas in today's industry.
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![GettyImages-2228948438 glycoprotein]( "From Black Box To Precision: A New Era Of Glycan Control")
Glycoprotein therapies face variable glycan profiles. An alternative approach, IVGE, moves modification outside the cell for true molecular control, ensuring consistency and speed.
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![GettyImages-181689527 cell culture]( "Proven Efficiency: Optimizing Cell Detachment With Recombinant GMP Trypsin")
Recombinant trypsin at optimized concentrations delivers effective cell detachment with reduced damage risk. Animal-free and GMP-compliant, it maintains high viability across multiple cell lines.
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![Roche - glycolysation brochure]( "Rethinking Glycosylation: A Primer On Enzymatic Control")
Discover how to gain precise control over one of the most common and critical forms of protein modification for therapeutic benefit and stability.
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![getty- 1299289706 -immunoglobulin-proteins]( "From R&D Tool To GMP Solution: Is Glycoengineering Ready For Your Plant?")
In this assessment of the in vitro glycoengineering technology we determine if it is suitable for the development, manufacturing, and analysis of therapeutic proteins.
SOLUTIONS
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![Roche - mycoplasma]( "What Activity Assays Miss: Detecting Inactive Trypsin Fragments In Final Formulation")
High-sensitivity immunoassays detect active and inactive enzyme residues at 0.5 ng/ml, addressing quality control gaps where activity-based methods fail to identify immunogenic protein fragments.
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![Roche -trypsin]( "Optimize Your Downstream Yield: The Purity Advantage Of Rec. GMP Trypsin")
Recombinant trypsin provides consistent β-trypsin ratios and animal-component-free production, reducing costs while improving biopharmaceutical manufacturing yield through self-catalytic activation.
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![Roche - FcRn]( "Mastering PK Control: Enhancing Pharmacokinetic Predictability With FcRn Affinity Tools")
Standardized affinity chromatography evaluates IgG-FcRn binding across pH gradients, revealing how structural variants and modifications impact antibody half-life for quality control applications.
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![Roche - proteases]( "The Pichia Advantage: Avoiding Endotoxin Risks In Recombinant CpB Sourcing")
Removing animal-derived materials from biopharma manufacturing doesn't have to mean compromising on enzyme performance, consistency, or regulatory readiness in critical production workflows.
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![Roche - IVGE]( "What If You Could Engineer Glycans After Purification?")
Variations in glycosylation can impact your therapeutic protein's safety and efficacy. Take control of this critical quality attribute with in vitro glycoengineering for predictable outcomes.
