ABOUT CYTOVANCE BIOLOGICS

Cytovance® Biologics is a biopharmaceutical contract manufacturing company specializing in the production of therapeutic proteins and antibodies from both mammalian cell culture and microbial fermentation. In addition to its cGMP manufacturing services, the company offers process development, cGMP cell banking and support services from its state-of-the-art Oklahoma City facilities.

Our Mission Statement
Cytovance® Biologics' mission is to become a valuable partner to our clients by providing an integral pathway in converting today's novel protein discoveries into future lifesaving therapies and diagnostics. Cytovance® is your partner in the biopharmaceutical contract manufacturing of therapeutic proteins and antibodies from mammalian cell culture and microbial fermentation.

At Cytovance®, we provide unparalleled support to biopharmaceutical companies to move new, safe medicines from the lab bench to those who need them most. We’re committed to a healthier world. Cytovance® offers a comprehensive range of development and cGMP manufacturing services, including:

FEATURED PRODUCTS

Cytovance® Biologics provides extensive mammalian and microbial pharmaceutical R&D service offerings that are both stand-alone and cGMP-enabling. Services include cell line development using Freedom® CHO-S® (Life Technologies), microbial strain development using GeneGPS Codon Optimization Technology (DNA2.0) and Cytovance® Biologics' Keystone Expression System™, research cell bank production, process development, process optimization using statistical Design-of-Experiments (DoE), technology transfer, scaled-down model development and process characterization using a QbD framework.

Cytovance® has a dedicated group that focuses on Expression Technologies using both Mammalian and Microbial systems. We offer our partners access to our proprietary, IP-free, royalty-free E. coliexpression platform, the Keystone Expression System® and to the mammalian platform using Gibco® Freedom® CHO-S® Kit from Life Technologies, a Thermo Fisher Scientific brand. Proper alignment of strain/cell line development with bioprocess development ensures efficient execution of your program. 

Cytovance® Biologics provides extensive mammalian and microbial pharmaceutical R&D service offerings that are both stand-alone and cGMP-enabling. Services include cell line development using Freedom® CHO-S® (Life Technologies), microbial strain development using GeneGPS Codon Optimization Technology (DNA2.0) and Cytovance® Biologics' Keystone Expression System™, research cell bank production, process development, process optimization using statistical Design-of-Experiments (DoE), technology transfer, scaled-down model development and process characterization using a QbD framework.

At Cytovance® Biologics Analytical Development Laboratory, we have the expertise to develop analytical methodologies and design testing plans to meet your individual product needs.  

Cytovance® has a 10+ year track record of successful technology transfer to support a wide range of biologics and clinical stages. Our core objective is to ensure that the contracted activities are well aligned with our clients’ objectives, whether they are focused on scale-up from early stage development phases to commercial manufacturing, expanding commercial scale to meet new market demand, or modifying the manufacturing process to improve process economics. Each customer project is customized to match the required scope and clinical phase. Commercial and in-house mammalian and microbial platform processes enable efficient movement through development programs and into commercialization. 

Cytovance® offers process characterization (PC) services to support product commercialization for in-house developed or established processes. Process Characterization studies are necessary to identify critical process parameters (CPPs), material attributes, control strategy, and design space. PC will justify the operating ranges and process control strategy for the scale-up process. 

CONTACT INFORMATION

Cytovance Biologics

800 Research Parkway, Suite 400

Oklahoma City, OK 73104

UNITED STATES

Phone: 405-319-8310

Contact: Beverly Crider, PhD.

FEATURED ARTICLES