Production Of Therapeutic Proteins In CHO Cells

Despite the widespread use of CHO cells in therapeutic protein production, the presence of many CHO cell line options and the need to optimize cell culture conditions for every cell line in a product-specific manner can lead to extended timelines and substantial cost in the development of a cell line for a new biologic. To meet this need, Cytovance has established a scalable platform process using the Freedom™ CHO-S™ expression system, which allows for rapid progression through the development pipeline into manufacturing and ensures a significantly reduced cost of development and shortened timeline from sequence to clinical material.