Newsletter | June 10, 2024

06.10.24 -- Survey: Most Biopharmas Expect To Adopt Perfusion Amid CM's March

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The biopharma space is full of big process intensification promises; increased capacity from smaller footprints, reduced raw material costs, improved sustainability, and measurable labor savings among them. What’s achievable, what batch processes are real-world biopharmaceutical manufacturers intensifying today, and what’s next on the path to continuous manufacturing? Find out by joining the discussion on June 11th. Registration for this live and interactive discussion is free!

FOCUS ON UPSTREAM MANUFACTURING

Survey: Most Biopharmas Expect To Adopt Perfusion Amid CM’s March

BioPlan Associates' 20th annual survey found that nearly three-fourths of biopharmaceutical companies expect to adopt upstream perfusion in most facilities.

 

Leveraging Efficiency From CLD To Clinical Manufacturing Of mAbs

Accelerate your biologic journey by discovering how our efficient strategies can propel your mAb from discovery to clinical manufacturing in as little as 18 months.

 

5 Ways To Increase Biomass In Your Shake Flasks

Optimizing the growth of cultures in a shake flask through a better understanding of these five factors can help you quickly and efficiently.

 

Metabolite And Nutrient Analysis For Optimal Upstream Processes

Discover how insights into cell metabolism can further enable the development of efficient cell culture processes through tailored nutrient supplementation and monitoring.

 

A Comparative Study Of Cryopreservation Media

This study compared two different cryopreservation mediums and the data highlights which is ideal for preserving the viability of different cell types, including Mesenchymal Stem and HEK-293 Cell Line.

 

Navigating Challenges In Immune Cell Therapy Analysis

During this panel, experts discuss the challenges faced by developers and manufacturers in the immune cell therapy field. These challenges include scalability, regulatory hurdles, and data standardization.

 

Spatial Biology: Learning The Landscape

Biological research is changing with a growing understanding of spatial biology, including the organization and interaction of molecules, cells, and tissues in their native spatial context.

 

Optimizing Scale-Up Of AAV Gene Therapy In Upstream Processing

Explore more detail on how to achieve a 2000L scale-up and studies that have been optimized through process characterization and experimental approaches to better understand key process steps.

 

A Tale Of Two Brothers: The Abpro Founders

By founding their latest venture, Abpro, Ian and Eugene Chan are using their synergistic skillsets in business and medicine to rapidly generate antibodies that treat cancer and autoimmune diseases.

 

SAR – Sequence-Activity Relationships for Efficient Protein Engineering

As protein-based therapeutics gain traction in the greater market, innovative techniques aimed at their optimization have become a key driver for industry.

 

Generation Of Stable CHO Cell Lines For Protein Production

By following the five steps of a specialized protocol, exceptional yields and stable cell lines can be achieved in CHO cells using antibiotic selection.

 

Accelerating Cell Line Development From DNA To Master Cell Bank

Cell line development is a complicated process, and partnering with a CDMO is an effective strategy to ensure these products are manufactured with speed and quality.

 

Benefit From Leveraging Perfusion Early In Process Development

By addressing the complex needs of cell culture from the start, organizations can take steps to optimize their process, ensuring they are maximizing productivity and product quality.

 

Bakuchiol Synthesis Optimization In S. Cerevisiae During Scale Up

Explore the significance of cost-effectiveness in synthetic biology and the successful scaling up of a process involving S. cerevisiae for the production of bakuchiol.

 

Real-Time Monitoring Of Key Bioprocess Parameters

The success of this experiment shows how the integration of Process Analytical Technology probes into bioreactors can enhance process understanding and enable precise bioprocess monitoring and control.

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Webinar: A next-generation medium and feeds system to improve productivity in CHO cell lines

Learn about the benefits of a next generation CHO medium and feeds system to support performance improvements in CHO-K1, CHO-K1 GS, CHO-S, and DG44 cells, including improved production capability and protein quality, sustained cell viability and more. Presenters will detail results from the use of this chemically defined offering designed with an innovative multi-omics based approach. Click here to learn more.

UPSTREAM MANUFACTURING SOLUTIONS

Cell & Media Kits - RoosterBio

SciVario twin Bioprocess Controller - Eppendorf SE

Corning CellCube System - Corning Life Sciences

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