Bakuchiol Synthesis Optimization In S. Cerevisiae During Scale Up From 250mL To 5L

By Vy Pham, Hannah Monroe, Melanie DeSessa, Kris Tyner, Jean-Marc Guedon, Kat Kozyrytska, Darcy Birse, Elena Cant

Explore the significance of cost-effectiveness in synthetic biology and the successful scaling up of a process involving S. cerevisiae for the production of bakuchiol. The scaling-up of this high-yield fermentation process was enabled by extensive bioreactor vessel characterization at Culture Biosciences, which facilitated troubleshooting and the generation of more material for subsequent operations.

Smoothly scaling 250mL fermentation process into 5L bioreactors, you can reduce costs associated with process development and enable the cost-effective production of natural products. This, in turn, can enhance market accessibility and commercial viability for manufacturers.