03.16.23 -- Single-Use Components For Closed System Manufacturing

For drug manufacturers, it’s critical to minimize the threat of contamination using a closed system during development and manufacturing. Learn about single-use connector options that can reduce many of the risks associated with tube welding while also meeting the sterility and reliability needs of your application.

As autologous cell therapies and other targeted gene therapies work to scale up to commercial levels, connections that can be changed out in seconds represent a distinct advantage for manufacturers. As a result, sterile aseptic connectors in small-batch processes are experiencing more widespread adoption, largely due to time and cost savings.

There is a strong debate taking place amongst manufacturers about whether aseptic connectors are superior to tube welding. As you work toward an educated decision, learn how factors such as hidden costs, system flexibility, training, and material considerations could tip the scales in favor of aseptic connectors.

When you’re focused on creating life-altering drugs worth millions of dollars, a simple fluid-handling connector can seem like a minor concern. However, without a reliable connector, your batch could quickly be rendered worthless. Explore three considerations to give you confidence when selecting fluid handling connectors for your bio application.

While a bioprocessing manufacturer may assume that every single-use system on the market undergoes a similar degree of rigor in its testing, the range and precision of these tests can vary widely between suppliers. Determining the best single-use systems to implement in a given manufacturing operation requires an understanding of both the process specifications and the capabilities of the component.