Building Reliability Into Bioprocessing – How Component Testing Improves Consistent Performance

By Andrew Quick, Test Lab Manager, CPC

While a bioprocessing manufacturer may assume that every single-use system on the market undergoes a similar degree of rigor in its testing, the range and precision of these tests can vary widely between suppliers. Determining the best single-use systems to implement in a given manufacturing operation requires an understanding of both the process specifications and the capabilities of the component. Transparency on the part of the component supplier is critical to achieving this understanding; bioprocessing companies should seek to partner with suppliers whose systems and components have undergone thorough testing – and have the results to prove it.

Vetting suppliers for their testing facilities, procedures, and documentation practices is crucial to ensuring that the components selected for a process are robust, sterile, and fit-for-purpose. Companies should expect component suppliers to perform certain tests, at a minimum, to validate these systems, and to provide the documentation verifying their performance up front. Customers should have a clear look at the functionality and performance characteristics of a connector or component before integrating it into a bioprocessing application. CPC, a global leader in single-use connection technology, has pioneered a testing process that offers users a comprehensive understanding of the key safety and reliability metrics of its products. This focus, coupled with its commitment to transparency in making its product’s testing profiles publicly available, position CPC to help the biopharma and cell and gene therapy industries to scale their processes seamlessly and confidently.