04.20.26 -- New Research: Co-Expression Could Make Plant-Based Systems Viable

Learn how to select the optimal manufacturing strategy and leverage technologies for efficient and scalable production of therapeutic proteins. De-risk the supply chain and accelerate time to market.

Explore how extracellular secretion and non-canonical amino acid incorporation create controlled conjugation sites on vaccine carrier proteins while simplifying purification and maintaining high-titers.

Process robust mAb production requires understanding scale dependent cell environments, leveraging predictive models, and pursuing data driven control to minimize variability and optimize quality.

Discover a high-efficiency workflow for isolating and expanding GFP-expressing HEK293 cells that enables stable, bright clones ideal for imaging and tracking to simplify clonal development.

Despite challenges with mammalian host cell line diversity, gain insight into mitigation strategies that drive efficiency and reproducibility, maximizing cell growth and product quality.

A common requirement for media and buffer preparation in biopharma processing is powder-liquid mixing. Review the performance of a 3000 L single-use mixing system for preparing aqueous solutions.

Address the rising gene therapy demands with an innovative perfusion strategy that significantly boosts cell density and viral vector yields to pave the way for scalable, efficient manufacturing.

Read about a next-generation transfection system that requires 50% less plasmid, decreases transfection reagent consumption, and yields higher AAV productivity to reduce cost per dose.