Newsletter | May 21, 2025

05.21.25 -- Incorporating AI Tools Into Downstream Process Optimization

SPONSOR

Webinar: Accelerate and Enhance Biomanufacturing Operator Training

Join Cytiva’s webinar to explore how a blended training approach—combining virtual reality, interactive eLearning, and onsite instructor-led sessions—can enhance operator performance and engagement. Learn how this strategy reduces human error, minimizes batch failures, and lessens dependence on internal experts. Discover how flexible, progressive training plans support continuous learning and help upskill both new hires and experienced staff in biomanufacturing environments. Click here to learn more.

FOCUS ON DOWNSTREAM MANUFACTURING

Incorporating AI Tools Into Downstream Process Optimization

Data-driven, hybrid modeling complements mechanistic thinking by reducing computational load for faster decision-making when time is a critical consideration.

Support Of Scale-Up, Tech Transfer Through Understanding Equipment

See how our expertise in formulation and process development can ensure a seamless scale-up from laboratory to full-scale production of lyophilized injectable products.

Collaboration For Clinical To Commercial Manufacturing Success

Begin your ADC manufacturing journey by finding a partner who can provide support through every phase of the conjugate life cycle, including process optimization, scale-up, and validation.

Introduction To mRNA Manufacturing

The SARS-CoV-2 virus has changed the course of scientific research around mRNA. Learn about mRNA manufacturing, the structure of a mRNA molecule, RNase-free considerations, and more.

Why Cell Washing Is The Hidden Bottleneck In Gene-Edited Cell Therapy

Scaling up life-saving gene-edited cell therapies means tackling production inefficiencies. Overcoming the time-consuming and risky cell washing step is crucial for clinical and commercial success.

Expansion Of Cord Blood-Derived CD34+ Cells In A Hollow-Fiber Bioreactor

CD34+ cells isolated from cord blood were expanded in a hollow-fiber bioreactor using a novel cytokine cocktail at one-tenth the standard concentration using a MSC-free coating strategy.

DOWNSTREAM MANUFACTURING SOLUTIONS

High Binding Capacity, Short Residence Time For Antibody Purification - W.L. Gore & Associates

Drug Manufacturing: Yield-Maximizing Technology - Argonaut Manufacturing Services

Sanitary Fittings: SF Series - Nordson MEDICAL

SPONSOR

Webinar: Seals & Stability: Preventing Failures in Synthesis and Chromatography Columns

This webinar highlights the overlooked importance of seals and O-rings in oligonucleotide synthesis and chromatography. Chuck Haeger shares real-world cases showing how proper maintenance and skilled teams prevent failures. Attendees will learn strategies to boost column longevity, reduce risks, and ensure high-quality output—ultimately supporting the production of life-changing medicines. Click here to learn more.

FOCUS ON FILL-FINISH

Forget About Isolators: Switching From Manual Vial To Automated Bag Filling

Discover how transitioning from manual vial filling to single-use bag systems can reduce contamination risk, improve accuracy, and enhance GMP compliance in biopharmaceutical manufacturing.

Fluid Connection Technologies For Sterile Fill And Finish Process Design

Single-use technology and innovative fluid connections play a significant role in creating an effective, sterile fill and finish operation that maintains the integrity of your biologic products.

SPONSOR

Webinar: Building a Purification Toolkit for an Expanding Variety of mAb Therapeutics

Join our webinar to discover how to build a versatile downstream processing toolkit, match diverse antibody formats to the right chromatography resins and buffers, and optimize purification workflows. Learn strategies to overcome the challenges of purifying complex molecules and achieve target purity and yield, helping you speed new biopharmaceuticals to market more efficiently.

FILL-FINISH SOLUTIONS

Container Closure Integrity Testing - Lonza

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