11.22.23 -- How To Lose A Batch In 10 Days

When implemented correctly using advanced analytics solutions, CPV can provide insights that help companies increase their productivity, reduce costs, and support iterative process improvements.

Drug product stability may be seriously compromised if mannitol completes crystallization during storage rather than during the freezing or annealing step in the lyophilization process.

Investigate important considerations for working with three different stem cell types: mesenchymal stem/stromal cells, induced pluripotent stem cells, and neural stem cells.

Defined control strategies enable more intensified and stable cell culture processes, such as perfusion, which may lead to dramatically improved productivity.

Recent advancements in genetic engineering, analytics, and screening reimagine E. coli as an “optimal” protein factory, not just a common one or an expression system artifact.

Diverse APIs and increased regulatory scrutiny are among the factors contributing to increased demand — and necessity — for microbial challenge studies to support IND submissions.

Explore the importance of implementing development approaches early in the product life cycle and how analytical method choice impacts the production of safe and efficacious gene and cell therapies.

Learn how a CDMO that is experienced in producing and characterizing diverse recombinant proteins is essential when accelerating the successful transfer of recombinant protein analytical assays.

Typically, mAb manufacturing takes up to 60 days due to demand and outsourcing lags. Instead, imagine a unified platform that can deliver your mAb in 18 days.

Explore how a purification development platform, with a mixed-mode chromatography step, enabled the acceleration of a biotherapeutics company's clinical trial supply while achieving high-quality material.

Three experts discuss the role and value of collaborations and what strategies can be used to help improve biomanufacturing resilience in an unpredictable but promising future.

Improve your cleaning and subsequent sterilization process for your bioreactors, ensuring a thorough cleaning, better reproducibility, and reduced labor.

Practical information on key issues including extractable/leachable testing in components, freeze/thaw in single-use assemblies, efficiencies driven by SUT advances such as genderless connectors, and more.

Designing bioprocessing consumables has become increasingly important in the single-use space as a way to address sustainability concerns.

Production of pure therapeutic DNA ONs requires efficient, scalable, and cost-effective chromatographic purification methods. This study explores a chromatography resin pairing to determine its effectiveness.