Newsletter | March 24, 2025

03.24.25 -- Host Cell DNA Impurities: A Unique Challenge For rAAV

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The rapid advance of ADCs has tested the fine balance between speed to IND and process development that stands up to the rigors of scale-up and transfer. Explore the processes leading ADC developers are employing to mitigate manufacturing-scale risk, and how automation and artificial intelligence are beginning to inform their work. Join Bioprocess Online Live for this interactive discussion. Registration is free thanks to the support of Thermo Fisher Scientific.

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Host Cell DNA Impurities: A Unique Challenge For rAAV

The potential safety impact of residual hcDNA remains largely unknown, but researchers at UCB are investigating to learn more and mitigate if necessary.

Innovations In Perfusion Bioprocessing

Gain valuable insight into the optimization and scalability of perfusion media and processes, driving progress in biotechnological processes for monoclonal antibody production.

New Innovations In Cell Line Development

Learn how you can overcome the challenges of cell line development including stable transfection, data management, media development, screening and monoclonality verification, and scale up.

Using Precision Fermentation To Produce Animal-Free Milk Proteins

Learn about an innovative approach to producing animal-free milk proteins using precision fermentation technology supported by bioreactors,  offering an ethical alternative to traditional dairy production.

A View From Experience In 3D Adherent Cell Culture For Advanced Therapies

For efficient, scalable, and cost-effective cell and exosome production, 3D cell culture is the answer. Learn how this advanced approach surpasses 2D limitations, unlocking new potential for therapies.

What Is Transfection?

Learn about the process of transfection and why it is crucial for studying gene function and has applications in various fields, including drug development and gene therapy.

Performance Of HEKima Adherent HEK Cell Medium

Explore the performance of a serum-free medium designed for HEK-293 cells, comparing its efficacy to traditional media for protein expression and cell proliferation.

hiPSC Aggregate Expansion In Stirred-Tank Bioreactors

Learn about a bioreactor-based Human Induced Pluripotent Stem Cell expansion workflow with the potential to improve cell therapy applications.

An Innovative Approach To Streamline Raman Implementation

Standard methods for building raman spectroscopy models are often time and resource-intensive. Explore one-batch calibration and how its performance compares to other modeling techniques.

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PDA Week 2025 Embracing Change: Catalysts for Disruption
06-11 APRIL 2025 | PALM SPRINGS | #PDAweek2025

Get ready for the event of the year! PDA Week 2025 is the premier annual homecoming event for the global pharma community. In today's dynamic industry landscape, PDA Week serves as the pharma community's anchor point for knowledge sharing, networking, and professional growth. Register Now

UPSTREAM MANUFACTURING SOLUTIONS

Vertical-Wheel Bioreactor: PBS-80 - PBS Biotech, Inc.

GS Effex Cell Line For Enhanced Antibody Effector Function - Lonza

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