02.28.24 -- Are Single-Use Technologies Always The Answer?

Explore how N-1 process development can lead to significant improvements in mAb production processes and review considerations for successfully implementing N-1 process development.

Read through five examples of how the right screening equipment helps achieve better results and avoid picking the wrong candidates.

Discover the impact revised pharmaceutical legislation will have on the industry by superseding regulations that have fostered the availability of safe and effective medicines for the past two decades.

Learn how digital standardized tools can simplify your scaling practices, help you better predict and visualize scaling needs, and reduce trial-and-error experimentation.

Review a study exploring the feasibility of scaling up 3 L of CHO culture to 30 L using single-use bioreactors without using multiple controllers or managing turnover with multiple runs.

Uncover guiding principles to ensure that your CGT supply chain is future-proof and learn how an agile, flexible approach can help advance your project with reduced costs and delays.

Learn more about a flexible freeze container that maintains package integrity after freezing at minus 86 °C. (minus 123 °F) through its durable design, minimizing product loss due to package failure.

Assessing outsourcing partners’ credentials in people, technology, supply chains, and integration will make all the difference as sponsors aim to streamline processes on the path to commercialization.

There are three major options when building a pharmaceutical grade cleanroom on your existing site — stick built, modular, or podular. Here, modular installation and stick built construction are compared.

Learn more about an effective, biodegradable solution for the viral inactivation process that controls protein impurities and is compatible with downstream unit operations.

Learn about the risk of endotoxin contamination in cell therapy products and how the LAL assay and recombinant endotoxin assays address these concerns to ensure the safety of cell therapy products.

Explore a manufacturing platform that integrates perfusion bioreactor technology; continuous product capture, low pH viral inactivation, and polishing steps; viral filtration, and formulation steps.

Rapid development of high-quality cell lines is vital to biomanufacturing projects. How developers approach the fundamental steps can define their core biologics capabilities and keep projects on track.

John Boehm discusses how single-use connections advance aseptic processing and create increased process flexibility and reliability while reducing costs.

Explore how a novel conjugation technology is enabling streamlined and cost-efficient production of antibody-drug conjugates (ADCs), driving the development of effective targeted cancer therapies.

To aid in the manufacturing of new vaccines, Pichia pastoris yeast, a promising protein expression system, could be the perfect solution.

Utilize these strategies to develop a functional equivalence model for single-use manufacturing equipment and assemblies for use in drug product manufacturing.

What sustainable manufacturing processes best address oligonucleotide environmental impact while maintaining scalability?

Learn how the expertise and resources of a strategic equipment management partner can optimize your resource recovery when selling equipment.