Newsletter | August 25, 2025

08.25.25 -- Abalone Bio's FAST Platform: How Does It Differ From Traditional Affinity Screening?

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Overcome workflow disruptions and contamination risks in open-vessel cultivation

Struggling with contamination and frequent workflow interruptions during open-vessel cultivation? Read this application note to learn how to reduce downtime, improve productivity, and achieve reliable, contamination-free cell growth for E. coli and CHO cells. The INFORS HT Multitron incubator shaker, featuring advanced HEPA filtration, rapidly establishes ISO Class 4 cleanliness, ensuring consistent, efficient lab operations.

FOCUS ON UPSTREAM MANUFACTURING

Functional Antibody Screening With Abalone Bio's Richard Yu, Ph.D.

In this episode of "Better Biopharma," Abalone Bio's CEO and co-founder, Richard Yu, Ph.D., explains how the company's functional antibody selection technology (FAST) platform differs from traditional affinity screening.

Addressing The Challenges In Lentivirus Harvest Clarification

Traditional depth filtration struggles with lentiviral harvest clarification, leading to low yields and high costs. However, single-use centrifugation offers a promising alternative.

Optimizing CAR T-Cell Development Starts With Your Cell Incubator

Explore how precise cell culture conditions are critical to advancing CAR T-cell therapies, which empowers researchers to develop more effective cancer treatments and accelerate breakthroughs.

Implementing Raman Spectroscopy For Automated Cell Culture Monitoring

Discover how Raman spectroscopy and parallel bioprocessing enable real-time cell culture monitoring, saving time and providing crucial data for process optimization in biopharmaceutical production.

Viral Vector Manufacturing Using Tangential Flow Depth Filtration

Address the rising gene therapy demands with an innovative perfusion strategy that significantly boosts cell density and viral vector yields to pave the way for scalable, efficient manufacturing.

New Innovations In Monoclonal Antibody Cell Line Development

Learn how innovations in automation and digitalization are transforming CLD, streamlining biologics production, and helping companies overcome challenges in next-generation therapy development.

Accelerate Your Path To The Clinic: Custom Cell Culture Media Solutions

A strategic approach to cell culture media is essential for success. Learn how to get a head start toward clinical readiness and avoid future hurdles with optimized media.

Achieve Higher AAV Productivity With A Next-Gen Transfection Reagent

Learn about a next-generation transfection system that requires 50% less plasmid, decreases transfection reagent consumption, and yields higher AAV productivity to reduce cost per dose.

Enabling Cell Line Tech Transfer For mAb Platform Manufacturing

Technology transfer, the transmission of bioprocess knowledge, skills and technology, is a crucial mechanism for ensuring adequate and timely access to innovative medicines.

Engineered Plasmids, Optimized HEK293 Cell Line Improves AAV Productivity

Low AAV productivity and lack of platform processes continue to be key challenges driving AAV production cost up. Explore a robust and scalable suspension manufacturing platform for AAV production.

iPSC Expansion In A Cell Expansion System's Small Bioreactor

Explore how using a flexible, automated system can help expand induced pluripotent stem cells (iPSCs) faster than traditional culture methods.

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Webinar: From Lab To Commercialization: Simplifying Bioprocess Scale-Up

Discover how Thermo Fisher Scientific’s DynaDrive™ Single-Use Bioreactors enable seamless scale-up from 1L to 5,000L. This webinar explores the cuboid design’s mixing advantages, real-world case studies, and strategies to overcome process development challenges. Learn how innovative geometry boosts flexibility, sustainability, and productivity for fed-batch and perfusion applications in process development, MSAT, and manufacturing. Click here to learn more.

UPSTREAM MANUFACTURING SOLUTIONS

CytoPak Products: Closed Process Solutions For Cell Therapy - ACROBiosystems

What If You Could Engineer Glycans After Purification? - Roche CustomBiotech

Advanced Tubing Retainers: Pharma+ - Nordson MEDICAL

CRISPR From Research To Therapy - Lonza

Maintaining Contamination-Free Cell Cultures In Open-Vessel Cultivation - INFORS HT

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