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UPSTREAM CELL LINE DEVELOPMENT

14:08 vips
VIPS™ For Cell Therapy: Updates

Watch to learn about the latest developments to VIPS™ which address the needs of cell therapy companies moving towards GMP manufacturing.

3:50 Millipore Lucie Grindes
Accelerate Identification Of High-Producing Cell Lines

When companies are putting in place an upstream process, a critical step is generation of a cell line expressing the protein of interest. Unfortunately, the search for the best-producing clone is often compared with looking for a needle in a haystack. Watch our video to l...

1:24 protein bio-synthesis GettyImages-1355122387
SF-RVN® Platform For Improving The Safety Profile Of Your Therapies

Discover how our Insect Cell Line provides a high performance platform optimal to produce recombinant proteins, viral vaccines, and adeno-associated vectors (AAV) for gene therapy applications.

1:42 CHO Fedbatch
CHO Fed-batch Portfolio: Cellvento® And EX-CELL® Advanced Media And Feeds

Cellvento® and EX-CELL® Advanced cell culture media supports consistent growth and performance from development to production. Get the enhanced performance, assured regulatory compliance and the security of supply necessary in today’s biopharmaceutical envir...

26:22 Advanced Instruments video 2
Clonality Based Workflows For Cell And Gene Therapy Laboratories

Watch Advanced Instrument’s presentation at the 5th Bioprocessing of Biotherapeutics, and explore four Solentim technologies that are designed for single cell cloning and assurance of monoclonality.

2:04 Thermo Fisher 2
How To Fill And Empty Nunc Standard Closed Cell Factory System

This video provides step by step how to instructions to fill and empty the Nunc Standard Closed Cell Factory System.

4:31 MilliporeCyrielle Corbin
How To Generate A High-Producing Cell Line In Fast-Track Mode

Cell line development processes can be quite time consuming and labor intensive. When our clients have a very challenging timeline, we can begin process development in parallel with cell line development, further accelerating timelines. What are the risks and how do you m...

1:38 GettyImages-1295492925-computer-future-data-research-lab
Is The Sensitivity Of Optical Biosensors Important?

Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.

27:28 Advanced Instruments video 3
Defining A New Ecosystem For Cell Line Development

In this presentation learn more about Solentim ICON™, the world’s first benchtop system for characterizing high productivity clones and STUDIUS™ software, the new standard for cell line development.

2:02 GettyImages-1127105013-lab-computer-research-scientist
Is Evaporation Important For Optical Biosensors?

If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?

32:06 Advanced Instruments video 4
Navigating The Workflow From Process Development To GMP Manufacturing For Making Clonal iPSC-Derived Master Cell Banks

In this video, we present data for optimizing choices of which combinations of GMP-compatible matrix, dissociation reagents, and media can best be employed for single cell cloning of iPSCs in process development.

34:24 Advanced Instruments Product launch
STUDIUS™ & ICON™: Data-Driven Workflow For The Development Of Modern Cell-Based Therapies

Learn how these two new products work to provide a new data-driven workflow for the development of modern cell-based therapies.

0:20 Maverick 1
Monitoring Multiple Bioprocess Parameters Right Out Of The Box

There’s no need to deal with complex empirical calibration models, reagents, or unreliable auto-sampling systems to implement in-line bioreactor monitoring.

3:18 Nunc Standard Closed Cell Factory System
Nunc Standard Closed Cell Factory System

This clean and closed system is designed to provide consistent and high-quality results to enhance your adherent cell culture processes. This ready-to-use system will help you quickly develop and scale up your processes with standard components for supply assurance.

3:13 Scientist examining microplate GettyImages-1387090964
Overcoming Cloning Inefficiencies To Accelerate New Protein Therapeutics

Watch as a scientist from Advanced Instruments demonstrates how the InstiGRO™ CHO cell culture supplement can be used to enhance clonal outgrowth during single cell seeding experiments.

1:57 Break Down Roadblocks To Clinical Success - Cell Line Development
Break Down Roadblocks To Clinical Success - Cell Line Development

Watch this video to learn the important decisions that each biopharma executive must make to break down roadblocks during the critical first step of cell line development and bring their molecule to clinic successfully.

1:24 Scientific testing research iStock-183764457
What's The Best Way To Choose A Mycoplasma Detection Strategy?

Mycoplasma contamination of cell cultures is a common and costly problem in biopharma, but ddPCR™ technology can help you save time and reduce risks of false positives.

0:20 Maverick 1
Raman-Based Monitoring Of Multiple Critical Parameters

Powered by Raman spectroscopy and a purpose-built de novo model, this platform performs simultaneous real-time measurements of multiple key process parameters in mammalian cell cultures.

3:04 Vips Pro
Solentim VIPS® PRO

Watch to learn how VIPS PRO optimizes your workflow productivity and provides complete confidence in single cell seeding and clonality assurance

1:57 science drug development data iStock-1209661917
Can Kinetics Provide Detailed Information About Binding Interactions?

See the potential value kinetics brings to deepen the understanding of biological processes.

0:52 Milliporesigma
Optimize Cell Culture Media

As you develop your upstream process, decisions you make today impact your titer and quality. But how can you maximize the performance of your cell lines?

3:01 Sartorius
How Biologic Therapeutics Are Developed

Scientists are harnessing the power of cellular machinery to produce therapeutic biologics that can target specific conditions. Learn about the process of developing a biologic treatment.

Understanding The Oligonucleotide Synthesis Process

Synthetic oligonucleotides are primarily used in therapeutics, as well as in diagnostic kits and PCR primers. This animation explains the repetitive four-step cycle of the oligonucleotide synthesis process.

1:03 Optimize Your Cell Culture Feed Strategy With Cellvento® ModiFeed Prime COMP
Optimize Your Cell Culture Feed Strategy With Cellvento® ModiFeed Prime COMP

This video shows how a new, easy-to-hydrate, single-part, pH neutral feed can support optimal cell growth and high productivity of CHO cell lines.

9:30 studius
The STUDIUS™ Powered Ecosystem

Watch to learn about the latest updates to the Solentim portfolio of products providing solutions to optimize your processes and increase confidence in your work.

2:08 Millipore
SAFC Cell Culture Solutions

The SAFC® portfolio is a full-service provider for all your upstream process development and cGMP manufacturing needs. Discover all the  capabilities of our SAFC® cell culture solutions and which of our products are the perfect fit for your project.

3:57 MilliporeClemence Justine
Increase The Titer Of A Difficult To Express Molecule

What happens if you have a promising molecule but can’t engineer a cell line to deliver the titer needed to support clinical development?  A low process titer may render the molecule, such as an antibody, too costly to manufacture and unsuitable for continued i...

2:07 Thermo Fisher 1
How To Fill And Empty Nunc Standard Cell Factory System

This video provides step by step how to instructions to fill and empty the Nunc Standard Cell Factory System.

1:57 Cytiva_46354_10061
Can You Run Crude Samples Using An SPR Instrument?

We explore a common misconception and provide examples of complex material being used in an SPR system.

6:22 Thermo impulse
Cytovance Customer Testimonial: Thermo Scientific Single-Use Technologies

Thermo Fisher Scientific has served as a key partner in the bioprocess industry, by establishing manufacturing and development capabilities, enabling Cytovance Biologics to expand offerings their product offering, to better serve clients with diverse pharmaceutical needs....