UPSTREAM CELL LINE DEVELOPMENT
Accelerate Identification Of High-Producing Cell Lines
When companies are putting in place an upstream process, a critical step is generation of a cell line expressing the protein of interest. Unfortunately, the search for the best-producing clone is often compared with looking for a needle in a haystack. Watch our video to l...
Clonality Based Workflows For Cell And Gene Therapy Laboratories
Watch Advanced Instrument’s presentation at the 5th Bioprocessing of Biotherapeutics, and explore four Solentim technologies that are designed for single cell cloning and assurance of monoclonality.
Is Evaporation Important For Optical Biosensors?
If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?
Raman-Based Monitoring Of Multiple Critical Parameters
Powered by Raman spectroscopy and a purpose-built de novo model, this platform performs simultaneous real-time measurements of multiple key process parameters in mammalian cell cultures.
Cytovance Customer Testimonial: Thermo Scientific Single-Use Technologies
Thermo Fisher Scientific has served as a key partner in the bioprocess industry, by establishing manufacturing and development capabilities, enabling Cytovance Biologics to expand offerings their product offering, to better serve clients with diverse pharmaceutical needs....
SF-RVN® Platform For Improving The Safety Profile Of Your Therapies
Discover how our Insect Cell Line provides a high performance platform optimal to produce recombinant proteins, viral vaccines, and adeno-associated vectors (AAV) for gene therapy applications.
Optimize Cell Culture Media
As you develop your upstream process, decisions you make today impact your titer and quality. But how can you maximize the performance of your cell lines?
Increase The Titer Of A Difficult To Express Molecule
What happens if you have a promising molecule but can’t engineer a cell line to deliver the titer needed to support clinical development? A low process titer may render the molecule, such as an antibody, too costly to manufacture and unsuitable for continued i...
How To Generate A High-Producing Cell Line In Fast-Track Mode
Cell line development processes can be quite time consuming and labor intensive. When our clients have a very challenging timeline, we can begin process development in parallel with cell line development, further accelerating timelines. What are the risks and how do you m...
CHO Fed-batch Portfolio: Cellvento® And EX-CELL® Advanced Media And Feeds
Cellvento® and EX-CELL® Advanced cell culture media supports consistent growth and performance from development to production. Get the enhanced performance, assured regulatory compliance and the security of supply necessary in today’s biopharmaceutical envir...
Is The Sensitivity Of Optical Biosensors Important?
Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.
The STUDIUS™ Powered Ecosystem
Watch to learn about the latest updates to the Solentim portfolio of products providing solutions to optimize your processes and increase confidence in your work.
Functional Antibody Screening With Abalone Bio's Richard Yu, Ph.D.
In this episode of "Better Biopharma," Abalone Bio's CEO and co-founder, Richard Yu, Ph.D., explains how the company's functional antibody selection technology (FAST) platform differs from traditional affinity screening.
How To Fill And Empty Nunc Standard Cell Factory System
Watch this step by step how to instructional video to learn how to fill and empty the Thermo Scientific Nunc Standard Cell Factory System, which is compatible with the same cell culture techniques used in smaller cell culture vessels.
Defining A New Ecosystem For Cell Line Development
In this presentation learn more about Solentim ICON™, the world’s first benchtop system for characterizing high productivity clones and STUDIUS™ software, the new standard for cell line development.
Overcoming Cloning Inefficiencies To Accelerate New Protein Therapeutics
Watch as a scientist from Advanced Instruments demonstrates how the InstiGRO™ CHO cell culture supplement can be used to enhance clonal outgrowth during single cell seeding experiments.
VIPS™ For Cell Therapy: Updates
Watch to learn about the latest developments to VIPS™ which address the needs of cell therapy companies moving towards GMP manufacturing.
Nunc Standard Closed Cell Factory System
This clean and closed system is designed to provide consistent and high-quality results to enhance your adherent cell culture processes. This ready-to-use system will help you quickly develop and scale up your processes with standard components for supply assurance.
Can Kinetics Provide Detailed Information About Binding Interactions?
See the potential value kinetics brings to deepen the understanding of biological processes.
Can You Run Crude Samples Using An SPR Instrument?
We explore a common misconception and provide examples of complex material being used in an SPR system.
Understanding The Oligonucleotide Synthesis Process
Synthetic oligonucleotides are primarily used in therapeutics, as well as in diagnostic kits and PCR primers. This animation explains the repetitive four-step cycle of the oligonucleotide synthesis process.
How Biologic Therapeutics Are Developed
Scientists are harnessing the power of cellular machinery to produce therapeutic biologics that can target specific conditions. Learn about the process of developing a biologic treatment.
SAFC Cell Culture Solutions
The SAFC® portfolio is a full-service provider for all your upstream process development and cGMP manufacturing needs. Discover all the capabilities of our SAFC® cell culture solutions and which of our products are the perfect fit for your project.
Break Down Roadblocks To Clinical Success - Cell Line Development
Watch this video to learn the important decisions that each biopharma executive must make to break down roadblocks during the critical first step of cell line development and bring their molecule to clinic successfully.
What's The Best Way To Choose A Mycoplasma Detection Strategy?
Mycoplasma contamination in cell cultures is a costly problem. Discover a rapid and accurate digital droplet PCR solution that minimizes false positives and meets pharmacopeia requirements.
Optimize Your Cell Culture Feed Strategy With Cellvento® ModiFeed Prime COMP
This video shows how a new, easy-to-hydrate, single-part, pH neutral feed can support optimal cell growth and high productivity of CHO cell lines.
Monitoring Multiple Bioprocess Parameters Right Out Of The Box
There’s no need to deal with complex empirical calibration models, reagents, or unreliable auto-sampling systems to implement in-line bioreactor monitoring.
How To Fill And Empty Nunc Standard Closed Cell Factory System
Watch this step by step how to instructional video to learn how to fill and empty the Nunc Standard Closed Cell Factory System, which is a closed system built with standard components to help ensure quality and assurance of supply.
STUDIUS™ & ICON™: Data-Driven Workflow For The Development Of Modern Cell-Based Therapies
Learn how these two new products work to provide a new data-driven workflow for the development of modern cell-based therapies.
Solentim VIPS® PRO
Watch to learn how VIPS PRO optimizes your workflow productivity and provides complete confidence in single cell seeding and clonality assurance