
UPSTREAM CELL LINE DEVELOPMENT

SAFC Cell Culture Solutions
The SAFC® portfolio is a full-service provider for all your upstream process development and cGMP manufacturing needs. Discover all the capabilities of our SAFC® cell culture solutions and which of our products are the perfect fit for your project.
Understanding The Oligonucleotide Synthesis Process
Synthetic oligonucleotides are primarily used in therapeutics, as well as in diagnostic kits and PCR primers. This animation explains the repetitive four-step cycle of the oligonucleotide synthesis process.

STUDIUS™ & ICON™: Data-Driven Workflow For The Development Of Modern Cell-Based Therapies
Learn how these two new products work to provide a new data-driven workflow for the development of modern cell-based therapies.

Solentim VIPS® PRO
Watch to learn how VIPS PRO optimizes your workflow productivity and provides complete confidence in single cell seeding and clonality assurance

Raman-Based Monitoring Of Multiple Critical Parameters
Powered by Raman spectroscopy and a purpose-built de novo model, this platform performs simultaneous real-time measurements of multiple key process parameters in mammalian cell cultures.

Navigating The Workflow From Process Development To GMP Manufacturing For Making Clonal iPSC-Derived Master Cell Banks
In this video, we present data for optimizing choices of which combinations of GMP-compatible matrix, dissociation reagents, and media can best be employed for single cell cloning of iPSCs in process development.

Defining A New Ecosystem For Cell Line Development
In this presentation learn more about Solentim ICON™, the world’s first benchtop system for characterizing high productivity clones and STUDIUS™ software, the new standard for cell line development.

Monitoring Multiple Bioprocess Parameters Right Out Of The Box
There’s no need to deal with complex empirical calibration models, reagents, or unreliable auto-sampling systems to implement in-line bioreactor monitoring.

SF-RVN® Platform For Improving The Safety Profile Of Your Therapies
Discover how our Insect Cell Line provides a high performance platform optimal to produce recombinant proteins, viral vaccines, and adeno-associated vectors (AAV) for gene therapy applications.

Cytovance Customer Testimonial: Thermo Scientific Single-Use Technologies
Thermo Fisher Scientific has served as a key partner in the bioprocess industry, by establishing manufacturing and development capabilities, enabling Cytovance Biologics to expand offerings their product offering, to better serve clients with diverse pharmaceutical needs....

How Biologic Therapeutics Are Developed
Scientists are harnessing the power of cellular machinery to produce therapeutic biologics that can target specific conditions. Learn about the process of developing a biologic treatment.

How To Fill And Empty Nunc Standard Closed Cell Factory System
Watch this step by step how to instructional video to learn how to fill and empty the Nunc Standard Closed Cell Factory System, which is a closed system built with standard components to help ensure quality and assurance of supply.

CDMO Hunger Games And The State Of Biotech With Siren Biotechnology's Nicole Paulk, Ph.D.
Biotech leader Nicole Paulk, Ph.D., joins “Better Biopharma” to discuss Siren Biotechnology’s switch from plasmids to producer cell lines, CGT funding challenges, and the competition that determined which CDMO won Siren’s busi...

CHO Fed-batch Portfolio: Cellvento® And EX-CELL® Advanced Media And Feeds
Cellvento® and EX-CELL® Advanced cell culture media supports consistent growth and performance from development to production. Get the enhanced performance, assured regulatory compliance and the security of supply necessary in today’s biopharmaceutical envir...

Is Evaporation Important For Optical Biosensors?
If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?

Optimize Your Cell Culture Feed Strategy With Cellvento® ModiFeed Prime COMP
This video shows how a new, easy-to-hydrate, single-part, pH neutral feed can support optimal cell growth and high productivity of CHO cell lines.

Nunc Standard Closed Cell Factory System
This clean and closed system is designed to provide consistent and high-quality results to enhance your adherent cell culture processes. This ready-to-use system will help you quickly develop and scale up your processes with standard components for supply assurance.

How To Fill And Empty Nunc Standard Cell Factory System
Watch this step by step how to instructional video to learn how to fill and empty the Thermo Scientific Nunc Standard Cell Factory System, which is compatible with the same cell culture techniques used in smaller cell culture vessels.

Overcoming Cloning Inefficiencies To Accelerate New Protein Therapeutics
Watch as a scientist from Advanced Instruments demonstrates how the InstiGRO™ CHO cell culture supplement can be used to enhance clonal outgrowth during single cell seeding experiments.

Optimize Cell Culture Media
As you develop your upstream process, decisions you make today impact your titer and quality. But how can you maximize the performance of your cell lines?

Can Kinetics Provide Detailed Information About Binding Interactions?
See the potential value kinetics brings to deepen the understanding of biological processes.

Functional Antibody Screening With Abalone Bio's Richard Yu, Ph.D.
In this episode of "Better Biopharma," Abalone Bio's CEO and co-founder, Richard Yu, Ph.D., explains how the company's functional antibody selection technology (FAST) platform differs from traditional affinity screening.

The STUDIUS™ Powered Ecosystem
Watch to learn about the latest updates to the Solentim portfolio of products providing solutions to optimize your processes and increase confidence in your work.

Efficient-Pro Medium And Feed (Why Choose Pro)
Discover an animal-origin-free and chemically defined medium and feed system solution designed to revolutionize your workflow.

VIPS™ For Cell Therapy: Updates
Watch to learn about the latest developments to VIPS™ which address the needs of cell therapy companies moving towards GMP manufacturing.

What's The Best Way To Choose A Mycoplasma Detection Strategy?
Mycoplasma contamination in cell cultures is a costly problem. Discover a rapid and accurate digital droplet PCR solution that minimizes false positives and meets pharmacopeia requirements.

Is The Sensitivity Of Optical Biosensors Important?
Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.

Clonality Based Workflows For Cell And Gene Therapy Laboratories
Watch Advanced Instrument’s presentation at the 5th Bioprocessing of Biotherapeutics, and explore four Solentim technologies that are designed for single cell cloning and assurance of monoclonality.

Can You Run Crude Samples Using An SPR Instrument?
We explore a common misconception and provide examples of complex material being used in an SPR system.