Upstream Cell Line Development

1. Overcoming Cloning Inefficiencies To Accelerate New Protein Therapeutics 10/24/2023

   Watch as a scientist from Advanced Instruments demonstrates how the InstiGRO™ CHO cell culture supplement can be used to enhance clonal outgrowth during single cell seeding experiments.

2. Clonality Based Workflows For Cell And Gene Therapy Laboratories 3/7/2022

   Watch Advanced Instrument’s presentation at the 5th Bioprocessing of Biotherapeutics, and explore four Solentim technologies that are designed for single cell cloning and assurance of monoclonality.

3. How To Fill And Empty Nunc Standard Cell Factory System 3/21/2022

   This video provides step by step how to instructions to fill and empty the Nunc Standard Cell Factory System.

4. Navigating The Workflow From Process Development To GMP Manufacturing For Making Clonal iPSC-Derived Master Cell Banks 3/7/2022

   In this video, we present data for optimizing choices of which combinations of GMP-compatible matrix, dissociation reagents, and media can best be employed for single cell cloning of iPSCs in process development.

5. Solentim VIPS® PRO 10/3/2022

   Watch to learn how VIPS PRO optimizes your workflow productivity and provides complete confidence in single cell seeding and clonality assurance

6. SF-RVN® Platform For Improving The Safety Profile Of Your Therapies 7/19/2022

   Discover how our Insect Cell Line provides a high performance platform optimal to produce recombinant proteins, viral vaccines, and adeno-associated vectors (AAV) for gene therapy applications.

7. Increase The Titer Of A Difficult To Express Molecule 12/11/2019

   What happens if you have a promising molecule but can’t engineer a cell line to deliver the titer needed to support clinical development?  A low process titer may render the molecule, such as an antibody, too costly to manufacture and unsuitable for continued investment. Learn how our client achieved a nearly 4-fold titer increase.

8. Optimize Your Cell Culture Feed Strategy With Cellvento® ModiFeed Prime COMP 4/1/2022

   This video shows how a new, easy-to-hydrate, single-part, pH neutral feed can support optimal cell growth and high productivity of CHO cell lines.

9. CHO Fed-batch Portfolio: Cellvento® And EX-CELL® Advanced Media And Feeds 3/11/2021

   Cellvento® and EX-CELL® Advanced cell culture media supports consistent growth and performance from development to production. Get the enhanced performance, assured regulatory compliance and the security of supply necessary in today’s biopharmaceutical environment.

10. Break Down Roadblocks To Clinical Success - Cell Line Development 12/27/2018

    Watch this video to learn the important decisions that each biopharma executive must make to break down roadblocks during the critical first step of cell line development and bring their molecule to clinic successfully.