DISCOVERY
GLP And The Impact To Start Up Companies
Good Laboratory Practice is often used in laboratories and is necessary for specific investigations. What does it mean? And how can it help start-up companies? Watch this video to learn more.
RNA Delivery Business with Liberate's Shawn Davis, Ph.D. & Walter Strapps, Ph.D.
Earlier this year, Shawn Davis, Ph.D. left a pretty comfortable position at AstraZeneca (and Amgen before that, and Milliken – and others – before that) to lead Liberate Bio. He brought along another industry notable in Merck/Intellia alumnus Walter Strapps,&n...
How To Best Optimize mRNA Production Workflows
Multiple steps in the mRNA manufacturing process can appear more complex than they have to be. Learn how to simplify your approach and produce the best possible mRNA vaccines and therapeutics.
LC/MS Method For Measurement In Human Plasma
According to the researchers, this plasma-based measurement has the potential to serve as a critical pharmacodynamic biomarker, facilitating the assessment of novel therapeutic approaches.
The NanoAssemblr® Spark™ Instrument Demo
The NanoAssemblr® Spark™ uses proprietary microfluidics technology for the controlled and reproducible manufacturing of nanoparticles in small volumes in less than 10 seconds.
Streamline Your mRNA Purification Steps
Ensure your mRNA's stability and effectiveness post-transcription with advanced filtration and chromatography techniques to enhance purity and recovery, which delivers high-quality mRNA for superior therapeutics and vaccines.
Saudi Arabia Government Leaders Discuss Agile Manufacturing Beyond Borders
Learn how government leaders in Saudi Arabia planned for biopharma resilience beyond borders and used agile manufacturing to prepare for the unknown.
Elucidating The Role Of IL-18 In NSCLC Integrated Analysis
Hear how imaging mass cytometry, CyTOF, and single-cell sequencing unlock the secrets of the tumor microenvironment. Discover new insights into IL-18 and its impact on non-small cell lung cancer.
Inside A Dopamine-Restoring Cell Therapy For PD With BlueRock Therapeutics' Dr. Amit Rakhit
On this episode of Cell & Gene: The Podcast, Host Erin Harris, invites BlueRock Therapeutics' Dr. Amit Rakhit to take a deep dive into therapy options for Parkinson's disease (PD). They discuss how BlueRock's bemdaneprocel's mechanism of action differs...
Nanoassemblr Blaze mRNA Vaccine Demo
NxGen Technology delivers a scalable means to perform the critical particle formation step in a nanomedicine development process.
Can Gene Therapy Be The Solution For CHF With AskBio's Dr. Lothar Roessig
Lothar Roessig, M.D., SVP, Integrated Product Team Lead, Congestive Heart Failure at Asklepios BioPharmaceutical, Inc. (AskBio) discusses the biggest challenges in developing gene therapies for cardiovascular diseases.
Can You Run Crude Samples Using An SPR Instrument?
We explore a common misconception and provide examples of complex material being used in an SPR system.
Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup
By leveraging this innovative combination, the assay achieves detection limits comparable to traditional methodologies while enhancing overall efficiency and reliability.
ResDNASEQ Workflow Solution
Explore the Applied Biosystems resDNASEQ workflow solutions. Starting with the sample preparation kit, to purification, quantitating residual host-cell DNA, and analyzing resDNASEQ assays.
STUDIUS™ & ICON™: Data-Driven Workflow For The Development Of Modern Cell-Based Therapies
Learn how these two new products work to provide a new data-driven workflow for the development of modern cell-based therapies.
How J&J Is Tackling Alzheimer's Disease With Fiona Elwood, Ph.D.
Fiona Elwood, Ph.D., VP and Neurodegeneration Disease Area Stronghold Leader at Johnson & Johnson, explains the company’s modality-agnostic approach to treating Alzheimer’s disease in this episode of Better Biopharma.
Real-Time Monitoring And Automated Sampling For Enhanced Efficiency
Integrating real-time, in-line monitoring with automated sampling in bioprocessing enhances efficiency and precision. Discover how advanced spectroscopy provides non-destructive insights to optimize cell growth and productivity.
Is The Sensitivity Of Optical Biosensors Important?
Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.
The NanoAssemblr® Spark™ Robust Low Volume RNA-Lipid Nanoparticle Formulation
Develop RNA-lipid nanoparticles (LNPs) in under 10 seconds for drug discovery and early preclinical development. The NanoAssemblr®️ Spark™ instrument enables rapid µL formulations to conserve limited and expensive ingredients with minimal waste....
Antisense Oligonucleotide Extraction Optimization Reveals Differences
Our findings provide critical insights into refining ASO extraction protocols, which can enhance the accuracy of downstream analyses and support further research into ASO-based therapeutics.
Functional Antibody Screening With Abalone Bio's Richard Yu, Ph.D.
In this episode of "Better Biopharma," Abalone Bio's CEO and co-founder, Richard Yu, Ph.D., explains how the company's functional antibody selection technology (FAST) platform differs from traditional affinity screening.
BoB@JPM: Gene Writing With Tessera's Michael Severino, M.D.
Flagship Pioneering plucked Michael Severino, M.D. away from AbbVie to run point at Tessera, a startup it's backed to pioneer a new category of genetic medicine it calls gene writing. The Business of Biotech caught up with Severino at the JP Morgan Healthcare Con...
Don't Be A D**k With Ochre Bio's Dr. Quin Wills
Don't be offended by the title of today's Business of Biotech podcast. Dr. Quin Wills' application of what's become known as "Wheaton's Law" (look it up) is central to the ambitious goals his company, Ochre Bio, is pursuing: pioneering the va...
Development Of A Mitra Tip Extraction Assay Coupled With LC-MSMS
Watch this rundown of a novel method for quantifying L-Citrulline, L-Arginine, and L-Argininosuccinic acid using Mitra tip extraction coupled with LC-MS/MS for enhanced accuracy and reproducibility.
Testing Liquid Handler Performance With PCRMix
We demonstrate the importance of using an appropriate test solution when optimizing a liquid handler to dispense the master mix, a critical component in any PCR-based assay.
An All-In-One Solution For Residual DNA Quantitation
Explore an all-in-one solution for residual DNA quantitation with a 3D lab tour with virtual demos, videos, and interactive instrument guides to experience the full workflow.
Tissue Adenosine Distribution-Guided Gene Selection
Unlike conventional predictive biomarkers, which often focus on isolated molecular markers, this strategy integrates spatial metabolomics and genomics, providing a multidimensional perspective.
Bio Career Moves With Codagenix's Johanna Kaufmann, Ph.D.
On this week's episode of the Business of Biotech, Dr. Johanna Kaufmann gives us an intimate retrospective on her career to date, sharing stories about her rapid ascension from Scientist 1 to executive leadership. We dig into her wild ride through M&A, her time at...
Developing Antibodies To Block Neuroinflammation With MindImmune's Stevin Zorn, Ph.D.
In this episode of "Better Biopharma," host Tyler Menichiello is joined by MindImmune's president and CEO, Stevin Zorn, Ph.D. They discuss the development of the company's lead candidate, MITI-101, a monoclonal antibody designed to prevent peripheral imm...
Is Evaporation Important For Optical Biosensors?
If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?