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DISCOVERY

1:02:28 24_01_BoB_1280x720_Ep171
Bio Career Moves With Codagenix's Johanna Kaufmann, Ph.D.

On this week's episode of the Business of Biotech, Dr. Johanna Kaufmann gives us an intimate retrospective on her career to date, sharing stories about her rapid ascension from Scientist 1 to executive leadership. We dig into her wild ride through M&A, her time at...

1:57 Cytiva_46354_10061
Can You Run Crude Samples Using An SPR Instrument?

We explore a common misconception and provide examples of complex material being used in an SPR system.

17:49 Bio-Expo Live
Real-Time Monitoring And Automated Sampling For Enhanced Efficiency

Integrating real-time, in-line monitoring with automated sampling in bioprocessing enhances efficiency and precision. Discover how advanced spectroscopy provides non-destructive insights to optimize cell growth and productivity.

59:16 24_01_BoB_1280x720_Ep168
Pragmatic Computational Biology with Andrew Satz

This week's guest on the Business of Biotech, EVQLV's Andrew Satz, says AI and ML in biopharma are like sex in high school. "Many of the people who say they're doing it really aren't, and the one who really are aren't talking about it," he sa...

1:02 Optimize Downstream For Your mRNA Template
Streamline Your mRNA Purification Steps

Ensure your mRNA's stability and effectiveness post-transcription with advanced filtration and chromatography techniques to enhance purity and recovery, which delivers high-quality mRNA for superior therapeutics and vaccines.

54:40 24_01_BoB_1280x720_Ep175
RNA Delivery Business with Liberate's Shawn Davis, Ph.D. & Walter Strapps, Ph.D.

Earlier this year, Shawn Davis, Ph.D. left a pretty comfortable position at AstraZeneca (and Amgen before that, and Milliken – and others – before that) to lead Liberate Bio. He brought along another industry notable in Merck/Intellia alumnus Walter Strapps,&n...

3:00 GettyImages-1089913166 lab
Development Of A Mitra Tip Extraction Assay Coupled With LC-MSMS

Watch this rundown of a novel method for quantifying L-Citrulline, L-Arginine, and L-Argininosuccinic acid using Mitra tip extraction coupled with LC-MS/MS for enhanced accuracy and reproducibility.

2:03 iStock-879831370-plasmid-lab-cell
The NanoAssemblr® Spark™ Instrument Demo

The NanoAssemblr® Spark™ uses proprietary microfluidics technology for the controlled and reproducible manufacturing of nanoparticles in small volumes in less than 10 seconds.

2:31 mRNA GettyImages-1356994723
How To Best Optimize mRNA Production Workflows

Multiple steps in the mRNA manufacturing process can appear more complex than they have to be. Learn how to simplify your approach and produce the best possible mRNA vaccines and therapeutics.

1:57 science drug development data iStock-1209661917
Can Kinetics Provide Detailed Information About Binding Interactions?

See the potential value kinetics brings to deepen the understanding of biological processes.

3:21 Artel
Testing Liquid Handler Performance With PCRMix

We demonstrate the importance of using an appropriate test solution when optimizing a liquid handler to dispense the master mix, a critical component in any PCR-based assay.

2:39 resdnaseq workflow
ResDNASEQ Workflow Solution

Explore the Applied Biosystems resDNASEQ workflow solutions. Starting with the sample preparation kit, to purification, quantitating residual host-cell DNA, and analyzing resDNASEQ assays.

1:48 LMSMS Analysis Of Coproporphyrin And Coproporphyrin III In Human Plasma
LC/MS/MS Analysis Of Coproporphyrin 1, Coproporphyrin 3 In Human Plasma

This innovative approach holds promise for reducing the need for extensive clinical drug-drug interaction studies, potentially streamlining the drug development process.

0:26 resDNASEQ Cinematic
An All-In-One Solution For Residual DNA Quantitation

Explore an all-in-one solution for residual DNA quantitation with a 3D lab tour with virtual demos, videos, and interactive instrument guides to experience the full workflow.

1:49 Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup
Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup

By leveraging this innovative combination, the assay achieves detection limits comparable to traditional methodologies while enhancing overall efficiency and reliability.

43:48 Functional Antibody Screening With Abalone Bio's Richard Yu, Ph.D.
Functional Antibody Screening With Abalone Bio's Richard Yu, Ph.D.

In this episode of "Better Biopharma," Abalone Bio's CEO and co-founder, Richard Yu, Ph.D., explains how the company's functional antibody selection technology (FAST) platform differs from traditional affinity screening.

1:38 GettyImages-1295492925-computer-future-data-research-lab
Is The Sensitivity Of Optical Biosensors Important?

Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.

2:40 GettyImages-1485067316 microscope
Elucidating The Role Of IL-18 In NSCLC Integrated Analysis

Hear how imaging mass cytometry, CyTOF, and single-cell sequencing unlock the secrets of the tumor microenvironment. Discover new insights into IL-18 and its impact on non-small cell lung cancer.

31:14 23_12_CGPodcast_1280x720_Ep91
Inside A Dopamine-Restoring Cell Therapy For PD With BlueRock Therapeutics' Dr. Amit Rakhit

On this episode of Cell & Gene: The Podcast, Host Erin Harris, invites BlueRock Therapeutics' Dr. Amit Rakhit to take a deep dive into therapy options for Parkinson's disease (PD). They discuss how BlueRock's bemdaneprocel's mechanism of action differs...

1:05:12 24_01_BoB_1280x720_Ep166
Bio & The Business Of Aging with Life Biosciences' Jerry McLaughlin

Core to the clinical-stage biopharma Life Biosciences belief set is that "contrary to popular belief, aging is not caused by random wear and tear, but instead is caused by a discrete set of biological mechanisms that can be targeted therapeutically.”

54:07 24_01_BoB_1280x720_Ep169
Don't Be A D**k With Ochre Bio's Dr. Quin Wills

Don't be offended by the title of today's Business of Biotech podcast. Dr. Quin Wills' application of what's become known as "Wheaton's Law" (look it up) is central to the ambitious goals his company, Ochre Bio, is pursuing: pioneering the va...

3:10 GettyImages-1346675624-lab-research
Nanoassemblr Blaze mRNA Vaccine Demo

NxGen Technology delivers a scalable means to perform the critical particle formation step in a nanomedicine development process.

2:02 GettyImages-1127105013-lab-computer-research-scientist
Is Evaporation Important For Optical Biosensors?

If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?

44:31 Developing Antibodies To Block Neuroinflammation With MindImmune's Stevin Zorn, Ph.D.
Developing Antibodies To Block Neuroinflammation With MindImmune's Stevin Zorn, Ph.D.

In this episode of "Better Biopharma," host Tyler Menichiello is joined by MindImmune's president and CEO, Stevin Zorn, Ph.D. They discuss the development of the company's lead candidate, MITI-101, a monoclonal antibody designed to prevent peripheral imm...

2:56 Milliporesigma
GLP And The Impact To Start Up Companies

Good Laboratory Practice is often used in laboratories and is necessary for specific investigations. What does it mean? And how can it help start-up companies? Watch this video to learn more.

2:01 908 Devices 3
Meet Your Bioprocess Sidekick For Cell Culture Media Analysis

You need rapid and reliable nutrient profiles to make informed decisions, and waiting on that data has detrimental effects on your process. See how REBEL fills the gap.

1:47 LC MS  Method For The Measurement Of Ornithine Carbamoyl Transferase Enzymatic
LC/MS Method For Measurement In Human Plasma

According to the researchers, this plasma-based measurement has the potential to serve as a critical pharmacodynamic biomarker, facilitating the assessment of novel therapeutic approaches.

21:08 23_12_CGPodcast_1280x720_Ep92
Can Gene Therapy Be The Solution For CHF With AskBio's Dr. Lothar Roessig

Lothar Roessig, M.D., SVP, Integrated Product Team Lead, Congestive Heart Failure at Asklepios BioPharmaceutical, Inc. (AskBio) discusses the biggest challenges in developing gene therapies for cardiovascular diseases.

1:57 Tissue Adenosine Distribution-Guided Gene Selection
Tissue Adenosine Distribution-Guided Gene Selection

Unlike conventional predictive biomarkers, which often focus on isolated molecular markers, this strategy integrates spatial metabolomics and genomics, providing a multidimensional perspective.

34:24 Advanced Instruments Product launch
STUDIUS™ & ICON™: Data-Driven Workflow For The Development Of Modern Cell-Based Therapies

Learn how these two new products work to provide a new data-driven workflow for the development of modern cell-based therapies.