Upstream Manufacturing Solutions

  1. Transforming Cell Line Development 6/9/2026

    An advanced cell line development platform using transposon integration and automated screening delivers rapid, high-yield, stable clones with reduced variability and consistent quality.

  2. Plant-Based Peptones For Bioprocessing 6/9/2026

    Plant-based, animal-free peptones enhance bioprocessing by improving yields, supporting low-serum conditions, simplifying media design, and enabling consistent and compliant cell culture performance.

  3. Strategic Use Of Yeast Extracts In Cell Culture 6/9/2026

    Animal-free yeast extracts enhance cell culture and fermentation by improving yields, cell health, and consistency, while supporting regulatory confidence, supply security, and media performance.

  4. Peptones, Hydrolysates, And Yeast Extracts 6/9/2026

    We offer plant-based, animal-free peptones, hydrolysates, and yeast extracts in ultrafiltered and microfiltered formats, supporting cell culture, fermentation performance, and bioprocess nutrition.

  5. 100% Animal-Free Production And Control 6/9/2026

    See animal-free peptones and hydrolysates enabling consistent, scalable cell culture and fermentation, with variability reduction, regulatory support, and customizable manufacturing solutions.

  6. GPEx® Lightning: Stable Cell Line Development For Complex Biologics 6/5/2026

    GPEx® Lightning delivers stable cell pools in 25 days, titers exceeding 15g/L for mAbs and 11g/L for bispecifics, and 60+ generations of stability — compressing timelines by 6–12 weeks.

  7. CHO Transient Production (TunaCHO® Process) 6/5/2026

    CHO cells have been the workhorse for protein and antibody manufacturing. The major advantages of CHO include robust growth, hardiness in suspension culture, stellar protein production and secretion, and a long track record.

  8. HEK293 Transient Production (Tuna293® Process) 6/5/2026

    HEK293 cells have been the most popular mammalian transient production platform. The primary advantage of HEK293 cells is transfection efficiency.

  9. Mammalian High-Throughput Production 6/5/2026

    The demand for high-throughput antibodies has exponentially increased over the last couple of years and has rapidly accelerated the antibody screening process.

  10. Madison: Clinical, Commercial Drug Substance Development 6/2/2026

    Catalent Madison offers gene-to-GMP drug substance in 8 months via GPEx Lightning CHO cell lines, hitting 15+ g/L, backed by 24 approved products and 5 GMP trains up to 4,000 L.