Upstream Cell Line Development

1. Overcoming Cloning Inefficiencies To Accelerate New Protein Therapeutics 10/24/2023

   Watch as a scientist from Advanced Instruments demonstrates how the InstiGRO™ CHO cell culture supplement can be used to enhance clonal outgrowth during single cell seeding experiments.

2. Monitoring Multiple Bioprocess Parameters Right Out Of The Box 10/4/2023

   There’s no need to deal with complex empirical calibration models, reagents, or unreliable auto-sampling systems to implement in-line bioreactor monitoring.

3. Optimize Your Cell Culture Feed Strategy With Cellvento® ModiFeed Prime COMP 4/1/2022

   This video shows how a new, easy-to-hydrate, single-part, pH neutral feed can support optimal cell growth and high productivity of CHO cell lines.

4. Understanding The Oligonucleotide Synthesis Process 1/24/2023

   Synthetic oligonucleotides are primarily used in therapeutics, as well as in diagnostic kits and PCR primers. This animation explains the repetitive four-step cycle of the oligonucleotide synthesis process.

5. Cytovance Customer Testimonial: Thermo Scientific Single-Use Technologies 12/8/2020

   Thermo Fisher Scientific has served as a key partner in the bioprocess industry, by establishing manufacturing and development capabilities, enabling Cytovance Biologics to expand offerings their product offering, to better serve clients with diverse pharmaceutical needs. In this video, the imPULSE Single-Use Mixer is highlighted for protein refolding applications at a 30 L scale and then transferred to manufacturing operations up to 5,000 L scale.

6. How To Fill And Empty Nunc Standard Closed Cell Factory System 3/21/2022

   This video provides step by step how to instructions to fill and empty the Nunc Standard Closed Cell Factory System.

7. SF-RVN® Platform For Improving The Safety Profile Of Your Therapies 7/19/2022

   Discover how our Insect Cell Line provides a high performance platform optimal to produce recombinant proteins, viral vaccines, and adeno-associated vectors (AAV) for gene therapy applications.

8. Can Kinetics Provide Detailed Information About Binding Interactions? 2/17/2022

   See the potential value kinetics brings to deepen the understanding of biological processes.

9. Accelerate Identification Of High-Producing Cell Lines 12/11/2019

   When companies are putting in place an upstream process, a critical step is generation of a cell line expressing the protein of interest. Unfortunately, the search for the best-producing clone is often compared with looking for a needle in a haystack. Watch our video to learn about our mini-pool approach and the value of automated systems to efficiently create, screen and isolate high producing clones with reduced costs.

10. Can You Run Crude Samples Using An SPR Instrument? 2/17/2022

    We explore a common misconception and provide examples of complex material being used in an SPR system.