Upstream Cell Line Development

  1. Defining A New Ecosystem For Cell Line Development 3/7/2022

    In this presentation learn more about Solentim ICON™, the world’s first benchtop system for characterizing high productivity clones and STUDIUS™ software, the new standard for cell line development.

  2. Overcoming Cloning Inefficiencies To Accelerate New Protein Therapeutics 10/24/2023

    Watch as a scientist from Advanced Instruments demonstrates how the InstiGRO™ CHO cell culture supplement can be used to enhance clonal outgrowth during single cell seeding experiments.

  3. Monitoring Multiple Bioprocess Parameters Right Out Of The Box 10/4/2023

    There’s no need to deal with complex empirical calibration models, reagents, or unreliable auto-sampling systems to implement in-line bioreactor monitoring.

  4. How To Fill And Empty Nunc Standard Closed Cell Factory System 3/21/2022

    Watch this step by step how to instructional video to learn how to fill and empty the Nunc Standard Closed Cell Factory System, which is a closed system built with standard components to help ensure quality and assurance of supply.

  5. CHO Fed-batch Portfolio: Cellvento® And EX-CELL® Advanced Media And Feeds 3/11/2021

    Cellvento® and EX-CELL® Advanced cell culture media supports consistent growth and performance from development to production. Get the enhanced performance, assured regulatory compliance and the security of supply necessary in today’s biopharmaceutical environment.

  6. Understanding The Oligonucleotide Synthesis Process 1/24/2023

    Synthetic oligonucleotides are primarily used in therapeutics, as well as in diagnostic kits and PCR primers. This animation explains the repetitive four-step cycle of the oligonucleotide synthesis process.

  7. Navigating The Workflow From Process Development To GMP Manufacturing For Making Clonal iPSC-Derived Master Cell Banks 3/7/2022

    In this video, we present data for optimizing choices of which combinations of GMP-compatible matrix, dissociation reagents, and media can best be employed for single cell cloning of iPSCs in process development.

  8. Raman-Based Monitoring Of Multiple Critical Parameters 10/4/2023

    Powered by Raman spectroscopy and a purpose-built de novo model, this platform performs simultaneous real-time measurements of multiple key process parameters in mammalian cell cultures.

  9. How Biologic Therapeutics Are Developed 8/26/2021

    Scientists are harnessing the power of cellular machinery to produce therapeutic biologics that can target specific conditions. Learn about the process of developing a biologic treatment.

  10. Accelerate Identification Of High-Producing Cell Lines 12/11/2019

    When companies are putting in place an upstream process, a critical step is generation of a cell line expressing the protein of interest. Unfortunately, the search for the best-producing clone is often compared with looking for a needle in a haystack. Watch our video to learn about our mini-pool approach and the value of automated systems to efficiently create, screen and isolate high producing clones with reduced costs.