Thermo Fisher Bioprocess Online Live Events
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Challenges And Considerations For Purifying Multispecific Molecules
5/20/2025
The structural complexity and variability of multispecific molecules presented purification challenges, from incorrect chain pairings to increased aggregation, fragmentation, and lower yield compared to standard mAbs. Developers shared how they overcame these challenges to achieve high purity and discussed key considerations for downstream developers when designing these processes. Bioprocess Online editor Tyler Menichiello explored these questions with Jian Ren, Ph.D., a principal scientist in downstream process development at AbbVie, and Mark Fitchmun, founder, president, and CEO of Somatek.
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Accelerating ADC Process Development
3/25/2025
The rapid advancement of ADCs put the fine balance between speed to IND and robust process development to the test, especially when scaling up and transferring production.
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Bioprocess Intensification In The Real World
6/11/2024
The biopharma “literature” is chock-full of big process intensification promises, but what is really achievable?
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IND Success: Navigate Through The Regulatory Gray
1/26/2023
Umoja Biopharma VP, Regulatory Affairs Helen Kim and NDA Partners' Expert Consultant Daniela Drago dig into the most common reasons for clinical holds, offer tips for avoiding and addressing them, and share best practices and resources for IND preparation in this special edition of Bioprocess Online Live!
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Early Process Considerations For Novel Protein Therapeutics
Complex protein-based therapies require developers to see the unforeseen and embrace new roles and responsibilities in sourcing both raw materials and outsourced expertise.