Process Engineering STREAM

  1. Enhanced API Solubility And Stable, High Drug Loads 4/12/2017

    Poor solubility of APIs is a critical challenge in drug development. One formulation technique to address this challenge is hot melt extrusion.

  2. Shaping The Future Of Process Intensification With Digital Solutions 10/3/2025

    Discover how automation, analytics, and AI are driving smarter process intensification and enabling a shift toward connected, continuous manufacturing.

  3. Creating Technical Debt When Experimenting With 3D Printed Parts 7/29/2026

    Companies need mature validation paradigms to recognize if and when it's time to transition from a prototype 3D printed part to a sustainable version, likely through a vendor-validated part.

  4. Five Reasons To Choose Single-Use Bioreactors 3/25/2026

    Explore five key advantages of single-use bioreactors, including scalable design, homogeneous mixing, broad chemical compatibility, and streamlined seed train processes for bioproduction success.

  5. A Case Study In 3D Printing: Shake Flask Jackets 7/29/2026

    While experimenting with a breathable shake flask for cell culture, Vikash Kumar, a process scientist now working at Merck, needed a way to control the oxygen and carbon dioxide permeating the flask wall.

  6. A New Era Of mAb Manufacturing 6/16/2025

    A medium and feed system designed to help you accelerate your work in bioprocessing and get to market faster.

  7. Training AI Models 9/17/2024

    In this segment from the Bioprocess Online Live, “A Realistic Look At AI/ML In Biomanufacturing,” panelists talk about what makes a good AI model and highlight considerations for training these models.

  8. Go Beyond Custom Media Screening And Prototyping 3/13/2026

    Learn about manufacturing solutions that streamline cell culture media scale-up with global production capabilities, equivalency strategies, and quality assurance for reliable supply.

  9. When And How To Implement Process Intensification 10/3/2025

    Explore when to intensify your processes, what challenges to expect, and how to prepare for a successful transition with expert insights to help guide your strategy and ensure smoother implementation.

  10. ADCs & Speed To IND 4/29/2025

    In this opening segment from the Bioprocess Online Live panel discussion Accelerating ADC Process Development, expert panelists Dr. Monika Lamba Saini (ADC Therapeutics), Dr. Léo Marx (Debiopharm), and Dr. Philipp Spycher (Araris Biotech) frame up ADC development challenges—including molecular complexity, regulatory and analytical hurdles, and strategic logistical manufacturing. We discuss those challenges in the context of the burgeoning industry’s breakneck development timelines leading up to IND submission.