Poor solubility of APIs is a critical challenge in drug development. One formulation technique to address this challenge is hot melt extrusion (HME). Our new Parteck® MXP is a polyvinyl alcohol-based excipient designed for hot melt extrusion to increase solubility and allow for stable and high drug loads for a broad range of APIs. The polymer has a long safety record related to its usage in drugs and is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration. Parteck® MXP complies with USP, Ph. Eur., and JPE monographs.