Insights On Polish & Viral Filtration

  1. Accelerating Biopharmaceutical Development From DNA To Drug 7/8/2016

    In the last decade, single-use solutions for virtually every bioprocess unit have been developed, and considerable investments have been made by the industry into areas that underpin this technology.

  2. Evolution Of Large-Scale Chromatography Column Packing 3/16/2016

    Chromatography has always played a crucial role in the purification of biologics. It has constantly evolved, and methods and capabilities have improved to reflect the industry requirements. This article gives an overview of how experience, innovation, and dialogue with customers led to the development of a platform that has revolutionized the economics of large-scale chromatography column packing.

  3. Accurately Quanitfy Capsid Protein Ratios

    Read how comprehensive monitoring of VP1, VP2, and VP3 protein concentrations and their molar ratios is an effective tool to ensure initial optimization and consistent quality of the final AAV gene therapy products.

  4. Determine The Optimal Media For An Efficient Purification Process

    In the purification of monoclonal antibodies, the separation of monomers from product-related impurities is a major challenge. Here, we highlight the importance of screening various media to determine the optimal one for an efficient purification process.

  5. Viral Contaminant Removal By Protein A Resin

    Protein A chromatography is capable of reducing the amounts of viral contaminants and can be utilized in downstream purification to support viral clearance for GMP manufacturing.