On-Demand Upstream Manufacturing Webinars

  1. Rapid Cell Culture Media Analysis For C> Process Development 6/3/2021

    Experts discuss how to accelerate process analytics with fast nutrient screening at critical time points and the benefits of rapid media analysis in cell therapy development and viral vector production.

  2. Accelerating Biologics Drug Development With An Analytical Toolkit 5/20/2021

    Using key attributes to monitor development processes can decrease timelines, improve product quality, reduce cost, and enable implementation of key knowledge gained from an analytical toolkit.

  3. Optimizing Upstream And Downstream Intensification 5/12/2021

    Sartorius expert Priyanka Gupta explains how intensified solutions for upstream and downstream processes can increase productivity by 4X and reduce upfront investment by 50%.

  4. Maximizing Product Titre By Strategic Control Of Osmolality In Mammalian Cell Bioprocesses 4/30/2021

    Osmolality is a key process parameter in mammalian cell bioprocesses that affects both specific cell growth and specific cell productivity. Published data shows that hyperosmolality, used in a targeted way at particular stages of the biological production process, for certain cell types, can enhance final product yield significantly. This presentation reviews the strategies that can be used to manipulate osmolality to increase production yields of monoclonal antibodies and other recombinant proteins.

  5. Upstream Applications Of Osmolality Testing In Cell & Gene Therapy Processes 4/30/2021

    This presentation focuses on the incorporation of osmolality testing into upstream applications which include media development, feeding strategies, and the minimization of aggregation.

  6. Drive Productivity By Tracking Key Nutrients In Your Bioreactor 4/29/2021

    Watch this on-demand webinar to learn about technological breakthroughs that now allow for rapid at-line analysis of cell media. You’ll learn the fundamentals about this new technology, how and why to track key nutrients in your bioreactor, how to adjust your feed strategy based on rapid insights, and how to monitor consumption trends to drive high productivity.

  7. Scale-Up Strategies: Mammalian, Microbial Process Commonalities 3/29/2021

    This webinar offers a general understanding of the concepts and tools required to successfully scale a process from bench to manufacturing.

  8. Developing Scalable Upstream Workflows For Recombinant And Viral Vaccine Processes 3/25/2021

    Vaccine manufacturing is responding to challenges for increasing safety assurance and responsiveness in order to reduce the impact of pandemic such as SARS-CoV-2. Therefore, in-depth knowledge of microorganism pathogenicity leads to develop new type of vaccines such as recombinant and viral vaccines. In this presentation we will review the current main upstream vaccine production processes, considering the choice of expression system, the means by which the biological preparation is introduced into the production cell and how Pall’s flexible single-use bioreactors support rapid process development, scale-up and safeguard the quality of life-protecting vaccines and help assure compliance with cGMP.

  9. The Future Of Osmolality Testing Within Cell & Gene Therapy 1/4/2021

    Learn more about our latest osmometers designed for process development while seamlessly transferring into GMP environments with advanced data management features (21 CFR Part 11) in this presentation, hosted by Kendal Studd, Applications Scientist.

  10. Designing Efficiency Into Your AAV Process 12/2/2020

    Meeting demand for high-quality adeno-associated virus requires scalable, cost-effective production. The process we developed optimizes each step from suspension cell culture to purified bulk.