Formulation Featured Articles

  1. Advancing Parenteral Manufacturing: The Role Of The RTU Container 10/12/2026

    Presterilized vials, syringes, and cartridges reshaped aseptic fill-finish around small batches and multi-format lines. Regulatory fit, material choices, and high-speed filling will define where the technology goes next.

  2. Bridging Discovery, Developability, And Commercial Reality 9/29/2026

    Driven by metabolic and oncology successes, the expanding peptide therapeutics market faces critical challenges requiring early, customized drug product development, stability, and safety strategies.

  3. Exploring The Genetic Tools Enabling Protein Expression In Fruit Flies 9/26/2026

    Fruit fly genetics enables precise, scalable protein expression through stable integration, targeted control, inducible regulation, and heritable systems.

  4. Engineering Better ADCs, Part 1: MoA, Conjugation Chemistry, And More 9/24/2026

    The field has evolved considerably in antibody–drug conjugate (ADC) science. In this first article of a two-part series, let's discuss how to engineer better ADCs, covering MoA, conjugation chemistry, and more.

  5. In Vivo Gene Editing Needs Robust Iteration, Not One-Time Optimization 9/22/2026

    Gene-editing performance depends on the interaction among editor design, RNA chemistry, guides, delivery, and biology. Learn why iterative optimization across the full system is essential.

  6. Can Targeted LNP Delivery Take In-Vivo CAR-T Therapy Beyond The Liver? 9/17/2026

    Achieving successful extrahepatic CAR T delivery with LNPs requires addressing the unique biological and technological barriers and designing targeting approaches that leverage innovative LNP design.

  7. Risk Managing Through The Void Of ATMP Visible Particle Guidance 9/8/2026

    Regulators expect cell therapy manufacturers to prove they control for visible particles, but guidance remains notably quiet on the matter. Companies must get creative or risk clinical holds.

  8. Looking Beyond Solubility And Process Performance 9/2/2026

    Solvent selection for spray-dried dispersions significantly impacts drug performance, scalability, and supply chains. Early, structured solvent choice is vital for successful manufacturing and commercialization.

  9. Expanding Subcutaneous Design Brick By Brick 8/14/2026

    Biologics are growing more complex. But what if the syringe itself could unlock new possibilities? Discover the technology “bricks” quietly reshaping subcutaneous drug delivery.

  10. Efficient Solutions Supporting Freezing And Storage Operations In Bulk Drug Manufacturing 8/13/2026

    Practical strategies for reducing handling steps, minimizing product loss risk, and improving operator efficiency in frozen drug substance cold chain operations.