Featured Articles
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AAV Process Intensification Using High Salt Lysis & Salt Tolerant Endonuclease
3/25/2024
Examine how intensifying AAV production with high salt lysis and Benzonase® Salt Tolerant endonuclease enhances viral yield and infectivity while ensuring DNA removal for patient safety.
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Contrast In Oligonucleotides
3/13/2024
Explore the differences between research-use-only oligonucleotides and those manufactured in compliance with GMP 21 CFR 820.
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Characterization Of Host Cell Proteins By Liquid Chromatography - Mass Spectrometry
2/26/2024
Explore an established liquid chromatography – tandem mass spectrometry (LC-MS/MS) method for characterization of residual HCPs in monoclonal antibody (mAb) products.
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Strategies For The Separation And Analysis Of Empty And Filled Capsids
1/23/2024
Explore approaches for the capture and separation of capsids, upstream strategies for reducing the level of empty and partially filled capsids, trends in AAV capsid design impacting purification, and more.
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Scalability And Performance Of MobiusĀ® iFlex Bioreactors
1/19/2024
Utilizing single-use bioreactors in intensified fed-batch and perfusion processes can help manufacturers produce a high-quality drug supply while reducing facility footprint and production costs.
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Perspectives On The Adoption Of Fully Closed Processing
1/16/2024
In this study, industry experts share their perspectives and plans related to the implementation of fully closed processing. Explore the drivers and challenges of fully closed processing and more.
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Streamlining And Enhancing Gene Therapy Production With Automation
1/9/2024
When it comes to determining the appropriate analytics to inform early development, there are a number of variables to consider surrounding cost, operator expertise, and throughput.
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Viscosity-Reducing Excipients For Protein Formulation
1/2/2024
Explore the viscosity-reducing abilities of excipients and excipient combinations, the impact of protein viscosity on injection force, and much more.
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Viscosity Reducing Excipients For Filtration Process Improvement
1/2/2024
We demonstrate two filtration methods evaluating the effect of the excipients in the Viscosity Reduction Platform on ultrafiltration processes used to produce a highly concentrated mAb formulation.
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Automated Aseptic Sampling For Upstream Bioprocessing
1/2/2024
Explore PAT, the use of automated sampling technology to accelerate analytical and quality control methods, the benefits of automated sampling in upstream process development, and more.