Downstream Processing Featured Articles

  1. AB SCIEX And Indigo Team Up To Accelerate Adoption Of Next-Generation Mass Spectrometry For Clinical Research, Forensic Toxicology And Clinical Trials 1/18/2012
    AB SCIEX and Indigo BioSystems recently announced an agreement to jointly market mass spectrometry solutions that streamline data acquisition and automate data review to ensure high quality results in clinical research and forensic toxicology as well as pre-clinical and clinical trials of new drugs.
  2. Crucell And Scripps Research Discover And Describe Broad-Spectrum Antibodies Against Influenza B, A Crucial Link In Development Of Universal Flu Therapies And Vaccine 8/9/2012

    In a landmark discovery, researchers from Crucell Holland B.V. and The Scripps Research Institute, recently announced the identification of the first human monoclonal antibodies that appear capable of disabling all influenza B viruses. 

  3. Article: How To Choose An Industrial Cation Exchanger For IgG Purification

    Cation-exchange chromatography is the third most used industrial method for antibody purification after anion-exchange and protein A affinity chromatography. It is most commonly used as an intermediate step but continues to attract attention as a capture method. By Pete Gagnon

  4. CellCentric And ZoBio Enter Into Partnership To Develop Lead Compounds Against Epigenetic Drug Targets 6/20/2012

    ZoBio and CellCentric are pleased to announce that the companies are working together to discover lead compounds against CellCentric’s portfolio of epigenetic therapeutic drug targets. ZoBio will use its proprietary TINS technology to screen its fragment library against targets nominated by CellCentric. Hit to lead and lead optimisation activities will be further supported by ZoBio’s biophysical and medicinal chemistry research services.

  5. 3M Purification Inc. Introduces New Zeta Plus Encapsulated, Single-Use Depth Filtration Products 5/4/2012

    3M Purification Inc. has expanded its portfolio of Encapsulated Zeta Plus single-use depth filtration capsules.  The two new product lines – Zeta Plus Scale-up Capsule Filters and new single-layer media grades for Zeta Plus Encapsulated capsules – are designed with our industry leading Zeta Plus depth filter media, designed for applications in the bio-pharmaceutical industry including cell culture clarification, downstream process protection, virus, DNA and lipid reduction, and host cell protein (HCP), protein aggregate, endotoxin and anti-foaming agent removal.

  6. Scientists Show Protein-Making Machinery Can Switch Gears With A Small Structural Change 11/15/2012

    For the past several years, Min Guo, an assistant professor at The Scripps Research Institute (TSRI), has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins.

  7. Genzyme Pioneering Continuous Manufacturing In Biotech 6/16/2015

    One company that has made significant progress in the development of a continuous manufacturing platform for large molecule drugs is Genzyme. I recently spoke with Jason Walther, a staff scientist at Genzyme, about the impact of continuous manufacturing on the industry as well as its potential. 

  8. Kimberly-Clark Professional Launches Innovative RightCycle Program To Recycle Single-Use Cleanroom And Laboratory Gloves And Garments 4/25/2013

    To provide cleanrooms and laboratories with effective solutions to mitigate waste and enhance Corporate Social Responsibility (CSR) and sustainability efforts, Kimberly-Clark Professional has introduced RightCycle – the first large-scale recycling effort for nontraditional cleanroom waste. 

  9. The Medicines Company And Bristol-Myers Squibb Begin Global Alliance For Recothrom® 2/8/2013

    The Medicines Company (NASDAQ: MDCO) announced today that the global license and two-year collaboration for Recothrom®, a recombinant thrombin approved by the U.S.

  10. Top Single-Use Suppliers Make Standardized Equipment A Reality – Part 2 5/8/2015

    Industry experts offer the benefits of standardized single-use equipment to both suppliers and users, as well as how it addresses some of the biggest objections to equipment standardization, as well as offer insight from the eyes of a user.