Downstream Processing Featured Articles

91. Article: How To Choose An Industrial Cation Exchanger For IgG Purification

    Cation-exchange chromatography is the third most used industrial method for antibody purification after anion-exchange and protein A affinity chromatography. It is most commonly used as an intermediate step but continues to attract attention as a capture method. By Pete Gagnon

92. Waters UltraPerformance Convergence Chromatography Ushers In New Category Of Separation Science At Pittcon 3/13/2012
    Waters Corporation recently drew back the curtain on several important new technologies and a new business venture at Pittcon 2012, the industry’s most important annual new product conference and exhibition.
93. Laser Spotlight Reveals Machine 'Climbing' DNA 10/26/2012

    The experiments, reported in this week's Science, use laser light to generate very bright patches close to single cells. When coupled with fluorescent tags this 'spotlight' makes it possible to image the inner workings of cells fast enough to see how the molecular machines inside change size, shape, and composition in the presence of DNA.

94. The Value of Closing Your Process

    For R&D and PD applications, closed, single-use systems can protect against both biological and cross-contamination, saving valuable research time and money.

95. New Monoclonal Antibody Developed That Can Target Proteins Inside Cancer Cells 3/13/2013

    Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer are buried inside cancer cells.

96. NIH-Funded Researchers Create Next-Generation Alzheimer's Disease Model 4/9/2013

    A new genetically engineered lab rat that has the full array of brain changes associated with Alzheimer’s disease supports the idea that increases in a molecule called beta-amyloid in the brain causes the disease, according to a study, published in the Journal of Neuroscience.

97. Element Six And The University Of Warwick Announce Development Of New Boron-Doped Synthetic Diamond Electrode For Extreme Electroanalysis Sensing Applications 3/18/2013

    AT PITTCON 2013, Element Six, the world leader in synthetic diamond supermaterials and member of the De Beers Group of Companies, recently announced that it has engineered DIAFILM EA (Electroanalysis grade) in collaboration with The University of Warwick.

98. LEWA Uses A Globally Exclusive License To HPLC Technology From Bayer Technology Services 6/12/2012

    Bayer Technology Services (BTS) is a well-known supplier of industrial chromatography products and services in the area of process technologies for the Bayer Group and for external customers. 

99. Forsyth Scientists Define The Bacteria That Live In The Mouth, Throat, And Gut 9/20/2012

    For the first time, scientists have defined the bacteria that inhabit multiple sites along the healthy human digestive tract in a large number of individuals. To prevent and control bacterial diseases, it is essential to first identify which bacteria are responsible for keeping us in good health.

100. Dr. Reddy's Laboratories Ltd. And Merck Serono Announce Collaboration To Develop And Commercialize Biosimilars 6/6/2012

     Dr. Reddy’s Laboratories Ltd. [NYSE:RDY] and Merck Serono, a division of Merck KGaA, Darmstadt, Germany, announced today a partnership to co-develop a portfolio of biosimilar compounds in oncology, primarily focused on monoclonal antibodies (MAbs). The partnership covers co-development, manufacturing and commercialization of the compounds around the globe, with some specific country exceptions.