Downstream Isolation and Purification

  1. Solutions For Diverse Biomolecule Purification 5/21/2025

    Interview with Paul Lynch, Product Management Leader, Purification, discusses our chromatography resins and innovations in downstream purification processes.

  2. Automated Bioburden Testing Solution 11/7/2025

    Automation is transforming microbial quality control labs, boosting productivity, minimizing errors, and ensuring data integrity. Discover how digitalization is driving Pharma 4.0 and reshaping lab workflows.

  3. Millipore Sigma Bio-Expo Live June 2025: Downstream Bioprocessing 7/3/2025

    Learn about the development and advantages of a new affinity ligand platform. It provides versatile, single-step purification for recombinant proteins and virus particles, enhancing yield and purity.

  4. Expanding Manufacturing Of Purification Resins To Align With Customer Demands 7/15/2025

    Discover how scaling up processes and building out facilities has allowed for end-to-end solutions that meet customer requirements for both supply and quality in their production lines.

  5. Perform Multiple Chromatography Steps On A Single System 2/26/2024

    The Resolute® BioSC platform is a highly modular multi-step chromatography system designed to purify biologics. The platform can be configured to design your own multi-step process.

  6. Productivity In mAb Capture 7/31/2025

    Discover how optimizing monoclonal antibody capture chromatography—especially resin selection—can dramatically improve cost efficiency, scalability, and productivity in therapeutic antibody manufacturing.

  7. A Scalable Immobilized Metal Affinity Chromatography Media For Process Purification 5/6/2021

    Downstream process purification of proteins requires a resin with optimized bead size for ideal pressure/flow properties and decent dynamic binding capacity DBC that provides production efficiencies and good process economics. This video explains how our newly developed metal chelate affinity resin — Nuvia IMAC — provides the mechanical strength, pore structures, ligand density, and particle size distribution required for an operation run at 300 cm/hr with a DBC of 40 mg/ml at 2 bar column backpressure.