Video

Virus Clearance By Chromatography

Bio-Rad hosts the Downstream Purification Workshop at BPI. Dr. Tareq Jaber from Charles River Laboratories presented the session, Virus Clearance by Chromatography, at this event. Chromatography is the main purification process in monoclonal antibodies (mAb) and recombinant protein (rProtein) products. Multiple chromatography steps also can be used to remove impurities including viruses. He presented the analysis of the over all performance of different chromatography types based on their internal database looking specifically for the log reduction factors for the most testable viruses; MuLV, MVM, PRV, and Reo-3. The following criteria were considered for building the database; MAB and rProtein studies, IND/BLA/feasibility studies, and different vendors resins/membrane with various specifications. This video is a summary of his session.

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