Downstream Filtration

  1. Sterilizing-Grade Filtration Of mRNA Encapsulated Lipid-Nanoparticles 9/2/2026

    Compare sterilizing-grade membrane performance at high and low pressures, including throughput, bacterial retention, and the effects of filtration on particle diameter and encapsulation efficiency.

  2. Role Of Membrane Chemistry And Filter Format In TFF 9/2/2026

    Compare hollow fiber and flat sheet TFF formats across three membrane chemistries, and see how filter selection can influence ambient-temperature UF/DF optimization, processing time, and quality.

  3. Enhancing mRNA-LNP Downstream Processing Via Single-Pass TFF 9/2/2026

    Single-pass tangential flow filtration effectively concentrates mRNA-LNPs and removes ethanol while maintaining quality. See how this approach produced LNPs with 4.2-fold higher in vitro potency.

  4. Improved Clearance Of Host Cell Proteins After Virus Inactivation 9/1/2026

    Learn how post-viral inactivation filtration can support precipitate and host cell protein removal while balancing throughput, purity and cost across different feeds and process development conditions.

  5. Considerations For Tangential Flow Filtration Process Development 5/27/2025

    Optimize your TFF process with single-pass technology by joining experts Mike Dango and Michael Brauchle as they share key strategies for scalable, efficient filtration process development.

  6. Considerations In Depth Filter Scale-Up 7/26/2024

    Explore study findings aiming to assist process development scientists and engineers in understanding the structure of depth filter capsules, identifying key parameters for development, and more.

  7. Virus Filtration: Regulations And Mechanisms 7/25/2024

    In this presentation, Dr. Nigel Jackson, Principal Engineer in R&D, offers an in-depth discussion on regulatory guidance and recent updates pertaining to virus filtration.