1. The Benefits Of Using Mixed-Mode Chromatography Sorbents In A MAb Purification Process

    The benefits of the unique selectivity and chemical stability offered by mixed-mode chromatography for the purification of monoclonal antibodies (MAbs) are well established. Rapid determination of optimum operating conditions earlier in process development maximizes the value of these industrial adsorbents.

  2. Pall Turns Continuous Bioprocessing Into Reality

    A future built from a solid history of biopharma innovation, where newly developed process steps offer end-to-end performance.

  3. An ADE-Derived Scale For Assessing Product Cross-Contamination Risk In Shared Facilities

    Beginning in 2004, a global team of pharmaceutical toxicologists, industrial hygienists, quality assurance professionals, a cleaning validation professional, and a representative from the US FDA participated in the development of the International Society for Pharmaceutical Engineering's (ISPE) Risk-Based Manufacturing of Pharmaceutical Products (Risk-MaPP) Baseline Guide.

  4. Large Scale Expansion And Differentiation Of Human Mesenchymal Stromal Cells

    Thermo Scientific™ Nunclon™ Delta treated Thermo Scientific™ Nunc™ Cell Factory™ systems is an effective format for the easy and rapid expansion of hMSCs. The Nunclon Delta surface is a fully synthetic chemical surface available with many options of sizes, shapes and surface area. hMSCs were removed from liquid nitrogen and plated directly onto the surfaces to be evaluated. T-25 cell culture flasks were used to determine the optimal seeding density prior to expansion of hMSC on larger formats.

  5. Praesto RoboColumns Datasheet

    Praesto RoboColumns are designed for easy process development and parameter screening, as well as for small scale purification or sample preparation.

  6. Praesto MiniChrom Columns Datasheet

    Process development is streamlined by using Praesto MiniChrom columns, pre-packed with your choice of Praesto modern, high flow Affinity or Ion Exchange resin, enhancing both time and cost savings of MAb platform processing.

  7. Praesto Base Matrices Datasheet

    Non-functionalized agarose chromatography beads – ideal base matrices for production of affinity resins or for gel filtration of large molecules such as viruses or plasmids.

  8. Praesto Chromatography Guide – Discover The Full Range Of Modern, High-Flow Agarose Resins

    For over 35 years, Purolite has supplied specialty ion exchange resin technology to industries within complex regulatory environments, including biotechnology, pharmaceutical, food, fine chemical and electric power generation. Purolite is the only global company to focus 100% on resin technology.

  9. Praesto Protein A Resins

    Modern, high flow agarose-based, alkaline-stable Protein A resins for cost-effective, high productivity MAb capture.

  10. Praesto Ion Exchange Resins

    Highly cross-linked, agarose-based ion exchange chromatography resins for efficient protein purification, from capture to polishing. Praesto SP (cation) and Praesto Q (anion) are designed for lab to process-scale purification of recombinant proteins and other biomolecules.