Downloads

31. Single-Use Clarification Across Process Scales 9/1/2026

    Gain insight into how combining centrifugation with targeted depth and chromatographic clarification can reduce filter demand, ease facility constraints, and support efficient mAb harvest.

32. Enhancing mAb Production: Advanced Downstream Purification Strategies 9/1/2026

    Explore how process optimization can address downstream mAb manufacturing bottlenecks, reduce labor and consumable costs, and support more efficient production without compromising performance.

33. Optimizing mAb Production: Upstream Process Intensification Strategies 9/1/2026

    See how integrated upstream and downstream intensification strategies can increase monoclonal antibody yield, streamline workflows, improve facility utilization, and reduce manufacturing costs.

34. How Cell Therapy's Fundamentally Different Model Impacts Patients 9/1/2026

    Examine the evolution of autologous CAR T therapies, their patient-specific manufacturing workflow, key similarities and differences with biologics production, and real-world approaches.

35. Viral Safety Considerations In Process Development 9/1/2026

    Explore how upstream media filtration and downstream anion exchange chromatography can work together to manage viral risk, strengthen AAV process development, and support reliable GMP production.

36. Genomic Medicine At An Inflection Point 9/1/2026

    In vivo therapies and streamlined ex vivo manufacturing are redefining genomic medicine. Understand the tradeoffs, priorities, and technical challenges influencing how future treatments are designed.

37. A Practical Roadmap For Column Sizing, System Selection, And GxP Readiness 9/1/2026

    Chromatography scale-up depends on aligning different factors. Learn which factors can help maintain process consistency, manage risk, and support the transition from development to manufacturing.

38. Faster Paths To Biosimilar Equivalence: Turning Guidance Into An Advantage 9/1/2026

    Evolving biosimilar guidance creates opportunities to reduce comparative clinical requirements through strong analytical evidence, risk-based justification, structure-function knowledge, and more.

39. Chromatography Polishing In The Age Of Intensification 9/1/2026

    As upstream processes intensify, chromatography polishing must handle higher loads and evolving impurity profiles. Modern strategies can improve clearance, extend resin life, and maintain throughput.

40. How Perfusion In Seed Train Bioreactors Can Simplify Upstream Processes 9/1/2026

    N-1 perfusion achieved approximately 95% viability while scaling from bench to production. See how this approach intensified seed trains without affecting subsequent fed-batch performance.