CARR Biosystems Featured Articles

  1. Accelerating The Seed Train: Enabling N-1 Intensification 1/15/2026

    Discover how N-1 intensification shortens production timelines and improves cell viability by replacing traditional filtration with automated, low-shear separation techniques to achieve higher seeding densities.

  2. Rebalancing mAb Clarification: From Depth Filter Dependence To Process Harmony 1/15/2026

    Learn how optimizing clarification workflows can reduce product loss and minimize buffer consumption by shifting primary workloads away from traditional high-capacity depth filtration systems.

  3. Modernizing Cell Banking: Scalable, Consistent, And Automated 1/15/2026

    Discover how automating cell banking workflows minimizes contamination risks and preserves viability in high-density cultures, ensuring consistent recovery and smoother scale-up.

  4. Enabling MSC Harvest, Wash, And Concentration 11/17/2025

    A study demonstrates how a low-shear, closed-system centrifuge achieved over 90% MSC recovery and minimized viability loss, supporting scalable cell therapy manufacturing.

  5. Media Exchange In iPSC Cell Expansion And Differentiation: A Comparative Study 11/12/2025

    Low-shear, closed-system media exchange in iPSC differentiation is vital for scalability. This study compares automated centrifugation to gravity sedimentation, showing equivalent or superior differentiation outcomes.

  6. Rethinking Capital Efficiency In Cell Processing 8/7/2025

    In cell processing, rigid, single-function equipment can lead to inefficiencies, wasted space, and scheduling conflicts. A versatile approach can help teams do more with less.

  7. Overcoming Scale-Up Challenges In iPSC Production: A Joint Investigation 6/26/2025

    Discover how new processing methods tackle challenges in large-scale stem cell production and how automated, low-shear processing maintains cell health and pluripotency across production scales.

  8. Smarter Cell Washing And Pre-Formulation For Allogeneic Therapies 6/26/2025

    Discover common pitfalls in cell washing and pre-formulation, including incomplete contaminant removal, manual handling, and throughput issues that compromise product quality and efficiency.

  9. Cell Harvesting: A Strategic Lever In Allogeneic Therapy Production 6/26/2025

    Current cell harvest techniques in allogeneic manufacturing face limitations, including scalability issues and cell damage. Learn why a shift in approach is vital for high-quality, efficient production at scale.

  10. Addressing The Challenges In Lentivirus Harvest Clarification 9/16/2024

    Traditional depth filtration struggles with lentiviral harvest clarification, leading to low yields and high costs. However, single-use centrifugation offers a promising alternative.