Biomanufacturing White Papers and Case Studies
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Liquid Retention Comparison In PC And PETG Containers
5/8/2020
Fluid retention is an important consideration when choosing a container. The physical design and material of construction of the container impact how much fluid remains after dispensing. Fluid retention is an important consideration when choosing which container to use. This application note is a comparison between different container products.
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Challenges In Bulk Drug Substance Logistics – Overcoming The Hurdles
4/15/2020
While technically simple to perform, the freeze-storage-thaw cycle comprises several mechanistic aspects that can compromise protein quality if not properly understood and addressed.
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Bulk Drug Substance Logistics – Primary Packaging
4/15/2020
There are currently many options of primary packages on how to transport the drug substance from A to B. This paper explains the benefits and shortcomings of a few of those options.
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Drug Substance Management With Single Use vs. Stainless Steel
3/2/2020
Fast freeze rates, safe storage and proper shipping of bulk drug substances are imperative. This case study compares the advantages and disadvantages of single-use systems and cryovessels.
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Clinical Supply Optimization: Enhanced Service Model Saves Client Time On Supplies
12/26/2019
The Vice President of manufacturing for a clinical-stage biopharmaceutical company faced an avalanche of work when a reorganization left him without a clinical supply manager. Planning to start 5 new clinical trials in 6 months while managing quality assurance, manufacturing, and supplies for new and ongoing studies, he turned to his Fisher Clinical Services account executive with a simple question: “How am I going to do all that?”
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Managing Clinical Ancillary Supplies At Global Scale
12/26/2019
Clinical ancillary management expertise helps biopharma company oversee a large, global trial from start through finish.
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Freezing And Thawing Of Protein Solution
12/19/2019
Parts of a protein solution will show less activity based on the stress it's exposed to during freezing and thawing. It's important to optimize the freezing and thawing process to minimize activity loss.
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Scalable Freeze And Thaw Platform For Pharmaceutical Bulk Drug Substance
12/19/2019
Did you know that slow freezing kills up to 20% of the protein solutions in biopharmaceutical liquids? This case study shows how fast freezing with a plate freezer reduces the risk of cryoconcentration dramatically.
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Advantages Of Single-Layer Film Vs. Multilayer Film In Bioprocessing
12/17/2019
Speed and flexibility are critical to succeed in the bioprocessing market. Plastics technology enables small-batch, single-use packaging solutions for customized drugs to serve a smaller patient population.
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Single-Use Technology In Frozen Bulk Drug Storage: The Cold Hard Facts
12/17/2019
This paper addresses the challenges of bulk drug substance storage, shipping, and other factors users must consider in deciding whether and how they will adopt the technology.