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| Mobius® iFlex Bioreactors for upstream processes are a scalable portfolio of stirred tank bioreactors that leverage single-use bags with enhanced strength, made with our innovative Ultimus® film. Perfusion applications are supported with ease by integrating a perfusion tower, that uses the Cellicon® Filter Assemblies to retain cells in the bioreactor vessel while removing spent media. Future-proof your process with modular flexibility, and request a demo or technical consultation with our experts today! |
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FOCUS ON UPSTREAM MANUFACTURING |
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A conversation with Arun Srivastava, Ph.D., University of Florida College of Medicine | AAV vectors composed of naturally occurring capsids are suboptimal. Gentle genetic alterations hold promise for safer, more efficient therapy. | |
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| Tackling Allogeneic Immunotherapy's Scale-Up Bottleneck | Application Note | PBS Biotech, Inc. | New bioreactor technology provides an optimal environment for shear-sensitive cells, addressing key scale-up challenges for allogeneic therapies from research to commercial production. |
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| Cell Line Development For Multi-Chain Biologics | Webinar | ATUM | Examine the application of a platform in creating CHO cell lines for manufacturing multi-chain biologics and the future considerations for 3-chain and 4-chain molecules, including chain ratio balancing. |
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| A Two-Part Strategy To Streamline The Path To FIH | Article | By Leslie Wolfe, Ph.D., and Shaunak Uplekar, Ph.D., KBI Biopharma | In cell line development, application of targeted integration cell line technology boosts development speed. Then, a proven production platform facilitates seamless scaleup to GMP manufacturing. |
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UPSTREAM MANUFACTURING SOLUTIONS |
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