Newsletter | March 20, 2025

03.20.25 -- Why You Should Consider AI-Powered Digital Twins For Smart Manufacturing

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The rapid advance of ADCs has tested the fine balance between speed to IND and process development that stands up to the rigors of scale-up and transfer. Explore the processes leading ADC developers are employing to mitigate manufacturing-scale risk, and how automation and artificial intelligence are beginning to inform their work. Join Bioprocess Online Live for this interactive discussion. Registration is free thanks to the support of Thermo Fisher Scientific.

FOCUS ON MANUFACTURING CONTROLS

Why You Should Consider AI-Powered Digital Twins For Smart Manufacturing

Digital twins replicate a physical system using real-time data from IoT sensors, industrial control systems, MES, LIMS, etc. AI-driven digital twins add an extra advantage of predictive maintenance.

Pathways To Bioreactor Process Scaling

Learn how digital standardized tools can simplify your scaling practices, help you better predict and visualize scaling needs, and reduce trial-and-error experimentation.

How A Global Pharma Manufacturer Reduced Line Stops And Increased OEE

Gain insight into how a leading pharmaceutical company identified the root cause of long-standing inefficiencies, optimized performance, and productivity with unprecedented speed and accuracy.

Biopharma Production And Quality Control With Electrophoresis

Discover how Kaneka Eurogentec, a leading provider of custom DNA synthesis and molecular biology service, enhanced their fragment analysis to achieve higher efficiency and accuracy in their workflows.

Enabling Digital Twins With Computational Fluid Dynamics Modeling

Embrace the transformative power of predictive modeling and digital twin technology to optimize bioprocess efficiency, ensure product quality, and drive innovation in biopharmaceutical manufacturing.

Innovations In Peptide Manufacturing

The peptide manufacturing industry is evolving to meet the demands of efficiency, scalability, and sustainability. Find out how the latest innovations are addressing these challenges.

Potency Assays 101: How To Develop A CMC Relative Potency Assay

Read about how to dissect the potency assay development process into its key steps, which offers a clearer understanding of the journey.

Symmetry Surgical Uses Software To Enhance Quality

Symmetry Surgical enhances operations and quality management using software to improve efficiency, compliance, and data-driven decisions while producing over 2 million surgical devices annually.

Rapid Thermal Stability Screening And Selection Of Monoclonal Antibodies

Attain knowledge about a differential scanning calorimeter that offers thermal stability screening of buffer formulations and protein sequence modifications.

Data Collaboration Driving CDMO Excellence, Product Innovation

See why CMOs and CDMOs who do not address the rising demand from life science clients for greater visibility in the manufacturing process risk falling behind.

Embracing AI In Digital Transformation: What You Need To Know

In the age of digital transformation, AI is no longer optional. Explore how to successfully integrate AI into your organization's operations for a competitive edge.

Asset Reinduction To Maximo EAM, Enabled By Reality Capture

Uncover how reality capture was used to create a digital twin 750,000-square-foot Pfizer campus to support asset reinduction to Maximo EAM, which saves Pfizer 3,000 hours per year.

Move Beyond Manual CQV Challenges With Digital Solutions

Review how digitalizing commissioning, qualification, and validation (CQV) with a new software streamlines processes, enhances compliance, and reduces time to drive efficiency and sustainability.

A Glossary For Industrial DataOps

The first step towards IT-OT collaboration is getting these functions to speak the same language. Here, we outline key Industrial DataOps terms and aim to establish a common dictionary for IT and OT.

Top 3 Life Sciences Compliance Strategies Every Startup Needs

Life sciences startups must integrate compliance early to ensure regulatory approval, and trust. Prioritizing compliance streamlines processes, and enables long-term success.

MANUFACTURING CONTROLS SOLUTIONS

Streamlining Bioconjugation For ADC Development - Abzena

Sample Quality Control (QC) Enhances Vaccine Sample Integrity - Agilent Technologies

Agile, Fully Integrated Continuous Processing - FUJIFILM Diosynth Biotechnologies

The Industrial DataOps Solution For Industry 4.0 - HighByte

Purpose-Built For The Modern Quality Management Ecosystem - ETQ

A Leading Digital Validation Platform For Life Sciences - Kneat Solutions

FOCUS ON FACILITIES DESIGN & MAINTENANCE

Adapting Single-Use Chromatography To Manufacturing Scale

Explore strategies for accommodating the ever-increasing upstream titers and volumes to prevent downstream purification from becoming a bottleneck.

Advanced Therapy Manufacturers' Checklist For Cleanroom Project Success

Current advances in cell, gene, and tissue therapies require a rethinking of how—and where—cleanroom manufacturing facilities could be built, which enables more options for sponsor process control.

Caramelization Of LSBIs Due To Extended Thermal Insult

Learn about liquid submersible biological indicators (LSBI), including the three basic LSBI formats, and how caramelization due to long sterilization cycles affects the media's ability to promote spore growth.

How Component Testing In Bioprocessing Improves Consistent Performance

Determining the best single-use systems to implement in a given manufacturing operation requires a thorough understanding of both the process specifications and the capabilities of the component.

Environmental Monitoring Handbook For Pharmaceutical Manufacturers

Acquire a thorough understanding of environmental monitoring, covering the fundamentals of particle counting and cleanroom designs, regulatory expectations regarding market release, and more.

A Checklist For Single-Use Sustainability In Virus Filtration

Single-use systems are critical to sustainable virus filtration. Discover a guide that will lead you to select the right equipment and outline the best practices for implementation.

Single-Use Technology In Pharmaceutical Manufacturing

Gain insight into the role of single-use technology in advanced therapy manufacturing, why pharmaceutical manufacturers are switching to disposable technology, and more.

Options And Challenges In Subvisible Particulate Contamination Monitoring

Examine the significance of minimizing particulate contamination in pharmaceutical and biopharmaceutical products produced through the use of single-use systems.

Labware Washing Techniques And The Sinner's Circle

Uncover labware cleaning techniques, comparing manual and automated processes, and how balancing the four factors of the Sinner’s Circle ensures effective, repeatable laboratory outcomes.

FACILITIES DESIGN & MAINTENANCE SOLUTIONS

Single-Use System For Clinical And Commercial Production Of LNPs - Cytiva

Advanced, Scalable, And Single-Use Automated Centrifugation Systems - Sartorius

Make Cleanroom Compliance Easy By Running Quick Reports - TSI Incorporated

Next Generation Sanitary Clamps - Nordson MEDICAL

A Technology For Unparalleled Cleanliness And Speed - AES Clean Technology, Inc.

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