Newsletter | May 18, 2026

05.18.26 -- Why Dilution Gets Tricky: The Role Of Measurement Variability

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Webinar: Simplifying ADC Analysis: Real-Time DAR and Concentration Measurement Without Dilution

Unlock faster, safer ADC development with smarter analytics. This Repligen webinar reveals how variable pathlength spectroscopy delivers real-time, accurate DAR and concentration data without dilution. Explore case studies showing reduced variability, minimized handling of potent payloads, and streamlined workflows. Learn how PAT-driven insights enhance process control, accelerate scale-up, and replace traditional UV-Vis methods for more consistent, efficient manufacturing outcomes. Click here to learn more.

FOCUS ON UPSTREAM MANUFACTURING

Why Dilution Gets Tricky: The Role Of Measurement Variability

Dilution's effects on downstream processes and final formulation is often understated. A statistical framework can quantify measurement uncertainty's impacts.

Solutions For The Clinical-Grade Manufacturing

Explore the crucial role of NK cells in the immune system and learn efficient methodologies for manufacturing gene-engineered NK cells and scaling up production.

Enabling Cell Line Tech Transfer For mAb Platform Manufacturing

Technology transfer, the transmission of bioprocess knowledge, skills, and technology, is a crucial mechanism for ensuring adequate and timely access to innovative medicines.

Why Is Custom Cell Culture Media So Important?

Customizing cell culture media is an important part of the early stages of development considering its composition is crucial for cellular therapeutics' success

CHO K1 Cell Culture Process Intensification For Enhanced Production

Discover how our optimized CHO K1 cell lines achieved up to an 80% increase in titer while maintaining product quality through molecule-specific process development strategies.

Understanding Adeno-Associated Virus Vector Impurities

AAV vectors hold promise for gene therapy, but removing product-related impurities remains a challenge. Learn how cell line development and process optimization are advancing rAAV production.

Advanced Technology Platform For Stem Cell-Derived Exosomes

Demand for EVs is rising due to their therapeutic promise. Examine two scalable platforms that address production challenges to support EVs' expanding clinical and commercial applications.

Where The Future Is Now In Life Sciences And BioPharma

Middlesex County, NJ, is a premier life sciences hub, attracting major biopharma leaders, entrepreneurs, and investors to accelerate global medical innovation.

Advancing Biologics Development With Next-Gen Cell Line Development

Next-gen CLD utilizes transposase-mediated integration for speed and stability and employs an engineered cell line to enhance ADCC and a high-throughput assay for early glycosylation control.

Large-Scale Exosome Production Stirred-Tank Bioreactors

Find out how engineered exosomes, displaying tumor-homing peptides, offer a promising tool for targeted cytotoxic drug delivery, produced efficiently with a bioreactor for critical research.

Engineered Plasmids And Optimized HEK293 Cell Line Improves Productivity

Low AAV productivity and lack of platform processes continue to be challenges, driving AAV production costs up. Uncover a robust and scalable suspension manufacturing platform for AAV production.

Rev-Up AAV Genome Production In Upstream Manufacturing

By increasing recombinant AAV titers, this AAV enhancer can help reduce upstream manufacturing costs and lower the cost per therapeutic dose.

A Highly Productive, Chemically Defined Exosome Media System

See how chemically defined media and optimized bioreactor protocols increase exosome yields 40-fold while reducing commercial manufacturing costs from $10,000 to under $1,000 per dose.

UPSTREAM MANUFACTURING SOLUTIONS

Sanitary Fittings For Single-Use Container Fluid Transport - Nordson MEDICAL

CHO Edge System - Asimov

Welders And Sealers That Deliver Dependable, Sterile Results - Terumo BCT

Advance The Potential Of Your Cell Culture - Roche CustomBiotech

Modular Platform For Adherent Cell Culture For Closed Systems - Corning Life Sciences

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