Corning® CellCube® Platform For Closed Systems

As the demand for cell and gene therapies and vaccine production intensifies, the transition from research to commercial manufacturing requires robust, scalable, and contamination-resistant solutions. Traditional adherent culture methods often face limitations in surface area and manual handling risks. Advanced modular platforms address these hurdles by utilizing a stack of parallel plates within a sealed environment, significantly increasing growth capacity without expanding the physical footprint.

By integrating continuous perfusion through a bioreactor and peristaltic pump, these systems ensure efficient gas exchange and uniform nutrient delivery. This automated approach maintains critical environmental parameters like pH and dissolved oxygen, which is vital for cellular health and consistency. Utilizing ready-to-use, sterile modules with specialized surface treatments further streamlines the workflow by eliminating complex in-house assembly and reducing validation timelines. Explore the modular configurations in the product overview brochure below to see how to optimize your scale-up process.