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| Webinar - Next-level cell lines: An integrated approach to biologic innovation | As AI and digital tools rapidly evolve, they are poised to reshape biopharmaceutical cell line development and subsequent manufacturing, overcoming inefficiencies in expression, scalability, and production. Join us to learn how a cell culture media platform and state-of-the-art biologics expression system routinely deliver high-titer clones (8–11 g/L) in 14 weeks for monoclonal and multispecific antibodies. |
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FOCUS ON UPSTREAM MANUFACTURING |
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By Katrina Cordovado, BioPlan Associates | New data from BioPlan Associates suggests single-use systems adoption may be plateauing with single-digit growth rates. | |
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| Advanced Technology Platform For Stem Cell-Derived Exosomes | Poster | By Elie Zakhem, Jae Jung, Cameron Garland, et al., RoosterBio and Lauren Torres, Mario Sinani, Carl Breuning, et al., Repligen | Demand for EVs is rising due to their therapeutic promise. Explore two scalable platforms that address production challenges to support EVs' expanding clinical and commercial applications. |
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| Enabling MSC Harvest, Wash, And Concentration | Case Study | CARR Biosystems | A study demonstrates how a low-shear, closed-system centrifuge achieved over 90% MSC recovery and minimized viability loss, supporting scalable cell therapy manufacturing. |
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| The Proven Supplement For CAR-T Solid Tumor Cytotoxicity | Application Note | By Asma Ayari, Ph.D., Nucleus Biologics | Optimize cell culture for solid tumor research. Replacing traditional serum can significantly enhance CAR-T cytotoxicity, improve consistency, and streamline the path to GMP-ready workflows. |
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| Chemically Defined HEK293 Viral Feed Boosts Viral Vector Production | Poster | By Shan Gao, Hamid Soleymani, Shahram Shahabi, et al., FUJIFILM Biosciences | Find out how a chemically defined viral feed can boost AAV titers by up to 8-fold, supporting multiple serotypes and both suspension and adherent HEK293 cell lines, simplifying scalability. |
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UPSTREAM MANUFACTURING SOLUTIONS |
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