Newsletter | October 2, 2024

10.02.24 -- Measuring Filter Performance—It's More Than Just A Label

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Webinar: Addressing the Challenges of Complex Biologic Purification - New Advances in Protein A Affinity Resins

Join the team from Ecolab, Purolite™ Resins on October 3rd as they discuss modern challenges in protein A purification, how strategic partnerships are benefitting technology innovation and Ecolab's affinity toolbox of chromatography resins. We will introduce Ecolab's next generation high-capacity protein A resin, DurA Cycle™ A50.

FOCUS ON DOWNSTREAM MANUFACTURING

How To Minimize The Impact Of Stability Testing On Gene Therapy Batch Yield

By BioPhorum

This article outlines strategies for reducing the volumes required for gene therapy stability studies, with the goal of conserving product for patients, while remaining compliant and delivering data on CQAs. 

Measuring Filter Performance—It's More Than Just A Label

Article | By Mark Ayles, Cytiva

How is the performance of a filter measured? Learn why the micron rating is an incomplete measure of filter performance, why the beta-ratio is a more accurate indicator, and more.

Immunoassays And Orthogonal Characterization

Article | By Alla Zilberman, Kerry Wooding, Jacob Stubbs, Jared Isaac, and Eric Bishop, Cygnus Technologies Inc.

Learn about host cell proteins (HCPs) along with how they are produced, their negative effects, how to identify HCPs in drug substances, and some technologies offering a solution for manufacturers.

Enabling Continuous Processing With Inline Buffer Formulation Systems

Webinar | Asahi Kasei Bioprocess

Dive into this exploration of the key obstacles to continuous processing, it's fundamental principles, and operational methodologies.

Evaluation of Lentiviral Vector Stability and Development

Application Note | Bio-Rad Laboratories, Inc.

Discover key findings that highlight the importance of evaluating LVV stability to develop a robust purification process. 

Addressing Host Cell Protein Challenges In Monoclonal Antibody Production

Article | By Yair Peres, Ph.D., Purolite, An Ecolab Company

A novel protein A-based agarose resin has been developed to address the challenges of host cell proteins (HCP) in monoclonal antibody production.

DOWNSTREAM MANUFACTURING SOLUTIONS

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Chromatography Membrane For Biomolecule Purification - MilliporeSigma

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Protein Capture Devices For Antibody Purification - W.L. Gore & Associates

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