Newsletter | January 20, 2025

01.20.25 -- Leveraging Directed Evolution To Optimize AAV Vector Design

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With a third wave of biologics patents expiring, the race is on to seize the booming opportunities in the fast-evolving biosimilars field. What’s driving the patent scramble? What hurdles in manufacturing, regulation, and market access must be cleared for biosimilars to thrive? And how are global industry leaders carving out strategies to dominate the market? Don’t miss Bioprocess Online Live happening February 4th. Registration is completely free, thanks to the support of Cytiva and Ecolab Life Sciences.

FOCUS ON UPSTREAM MANUFACTURING

Leveraging Directed Evolution To Optimize AAV Vector Design

4D Molecular Therapeutics (4DMT) CEO and co-founder, David Kirn, MD, talks about the company’s approach to vector optimization, its product development, and its stage-appropriate buildup of internal GMP manufacturing.

Stable Bulk Cultures: A Fast Path To Antibody Manufacturing

The potential advantages that stable bulk cultures can offer a drug development paradigm are poised to accelerate and bolster biopharmaceutical clinical manufacturing.

What To Look For In A Cell Culture Media Supplier

Choosing a cell culture media supplier is crucial in biopharmaceutical manufacturing. Explore five key factors to take into account when choosing a supplier and evaluating their capabilities.

Why Use Transposase Technology For Expression Of Your Biotherapeutics?

Discover how a proprietary transposase technology works and why it can be beneficial for the development process for the expression of biologics.

Are Bioreactors The New 'Fish Tanks'?

By exploring innovative approaches to scaling up animal cell growth in cutting-edge bioreactor systems, foodtech companies are poised to offer healthier, safer, more sustainable fish for consumers.

Overcome The Limitations Of Conventional Transfection With Electroporation

Learn how electroporation technology improves gene editing efficiency, reduces cell death, and enables scalable workflows for cell therapy, screening, and bioproduction in this informative webinar.

Why Is Custom Cell Culture Media So Important?

Customizing cell culture media is an important part of the early stages of development considering its composition is crucial for cellular therapeutics' success

Manufacturing Strategies And Facility Design For Patient-Centric Delivery

Find out how to select manufacturing strategies and leverage technologies for efficient, scalable production of therapeutic proteins. De-risk the supply chain, accelerate time to market, and reduce costs.

An Innovative Approach To Streamline Raman Implementation

Standard methods for building Raman spectroscopy models are often time-consuming and resource-intensive. Explore one-batch calibration and how it compares to other modeling techniques.

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Nanotechnology To Improve The Performance Of Your Small And Large Molecule Medicines

Christian Jones shares the latest in nanotechnology advancements including recent clinical data, formulation applications, and API optimization to NanoImprove formulations through superior bioavailability, drug loading, route of administration, pill burden, and more.

UPSTREAM MANUFACTURING SOLUTIONS

Sanitary Fittings: SF Series - Nordson MEDICAL

CHO Host Cell Protein ELISA Kit, 3rd Generation - Cygnus Technologies Inc.

CRISPR From Research To Therapy - Lonza

Single-Use Bioreactors With Vertical-Wheel Technology - PBS Biotech, Inc.

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Registration for INTERPHEX 2025 is officially live! Happening April 1-3 in NYC, INTERPHEX is the largest pharmaceutical and biotechnology event of the year. Join over 9,000 industry professionals and 500+ exhibitors from all over the world as we take you through the entire pharmaceutical product development lifecycle. Follow the link to claim your FREE Exhibit Hall badge: http://interphex25.com/INT25LSC

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