Newsletter | January 13, 2025

01.13.25 -- Internalizing Nanoparticle Therapeutic Development

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Let Us Handle Your Buffer Preparation

Thermo Fisher Scientific is here to support you with the buffer preparation in your manufacturing workflow. Leaving the non-core activities to us enables you to focus on the patient therapy development. Our capabilities cover off-the-shelf products like WFI, NaOH, NaCl, or EtOH, a library of the most frequently used buffers that are made-to-order, as well as fully customized buffers.

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Internalizing Nanoparticle Therapeutic Development

De facto approaches to treating immune-mediated diseases aren’t very kind to the immune system itself. COUR Pharmaceuticals is leveraging nanoparticles, a purpose-built platform and in-house expression systems to build antigen-specific therapies that treat the root cause of autoimmune diseases.

Support The Culture Of Adherent Vero Cells With A Serum-Free Medium

This study compares a serum-free medium to other commercially available pre-hydrated media to measure its effectiveness in supporting the culture of adherent Vero cells.

The Advantages Of Tubular Bowl Centrifuges In Media Exchange

Learn about the application of tubular bowl centrifuge technology in cultivating induced pluripotent stem cells (iPSCs) for regenerative medicine.

Development For eCB-MSCs On Microcarriers In Vertical‐Wheel Bioreactors

Dive into this examination of the bioreactor culture of equine cord blood mesenchymal stromal cells (eCB-MSCs) using microcarriers for enhanced cell yield, reproducibility, and homogeneity.

5 Ways To Increase Biomass In Your Shake Flasks

Optimizing the growth of cultures in a shake flask through a better understanding of these five factors can help you quickly and efficiently.

A Different Approach To Adeno-Associated-Virus (AAV) Clarification

Knowledge of the feed stream, process constraints, and goals, makes selecting depth and membrane filter combinations for preliminary bench-scale filterability studies possible.

Ex Vivo Expansion And Differentiation Of Erythroblasts

Compare and contrast the performance of two stirred bioreactor types during the expansion of erythroblast cultures when a repeated batch cultivation strategy was used.

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Webinar: Quality Roundtable: Raw Material Planning for Tech Transfer and Scaling Biologics

Join fellow biopharmaceutical professionals as they discuss strategies for transitioning biopharmaceuticals from research to clinical and commercial manufacturing. Topics include overcoming tech transfer challenges, vendor certificates of analysis, raw material selection, process performance qualifications, regulatory requirements, and inventory management. The panel will address questions on these key areas to help navigate quality and planning decisions in biologic progression. Click here to learn more.

UPSTREAM MANUFACTURING SOLUTIONS

X-Platform Bioreactor Video - Cytiva

An Innovative Automated Clone Screening System - Danaher Life Sciences

Cell Culture Media & Supplements - RoosterBio

Quantum Flex Cell Expansion System - Terumo BCT

Integrated Cell Line Development Solutions - Aragen Bioscience, Inc.

Cell Line Development Solutions - ATUM

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