Newsletter | June 19, 2026

06.19.26 -- Inside AstraZeneca's Fully Electrified Cell Therapy Facility

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Webinar: From Variable to Predictable: How Intensified Upstream Processing Improves Scale-Up and Tech Transfer

Discover how intensified upstream processing can help biomanufacturers boost productivity, reduce variability, and accelerate timelines without compromising quality or compliance. In this webinar, Thermo Fisher Scientific experts share practical strategies for high-density inoculation, perfusion, automation, PAT, and data-driven control to improve consistency, streamline scale-up, and enable reliable tech transfer across development and GMP manufacturing. Click here to learn more.

FOCUS ON SUPPLY CHAIN

Inside AstraZeneca's Fully Electrified Cell Therapy Facility

The company won an ISPE FOYA for its Rockville, Maryland, manufacturing site that boasts 100% uptime and flexible capacity to produce thousands of batches annually.

A Hub For Life Sciences Drug Development

Middlesex County, NJ, is a hotbed for the life sciences, offering a deep talent pool, an extensive R&D presence, and dedicated backing by local government in the form of strategic investment.

Deep Interpretation Of GMP Product Quality

Explore the critical aspects of GMP-grade raw materials in CGT manufacturing, including contamination control, aseptic strategies, quality systems, supply chain security, and regulatory compliance.

Trends In Cold Chain Storage For Biologics

Packaging is critical, as biotechnology products requiring colder storage become more valuable. Find out how you can improve your temperature-controlled supply chain and meet cold chain storage demands.

The Future Of RNA Manufacturing Starts With Raw Material Innovation

Amid the mRNA and oligonucleotide therapeutic boom, sponsors and manufacturers are uncovering how to make raw materials—capping agents, lipid nanoparticles, and RNA polymerase—more effective.

SUPPLY CHAIN SOLUTIONS

Flexible Freeze Containers - W.L. Gore & Associates

FOCUS ON PROCESS ENGINEERING

Application Guide: Normalization Handbook

Gain insight into how to choose and validate normalization strategies for western blots, avoid common pitfalls, and ensure reproducible results using proteins tailored to your experimental context.

The Most Exciting Frontiers In Cell Therapy Development

From high-dimensional profiling to customizable Omic panels, new technologies are redefining cell therapy development—delivering better insights, efficiency, and scalability for researchers worldwide.

Fluid Management In HPAPI Manufacturing

Discover how closed-system approaches in HPAPI and ADC manufacturing reduce operator exposure, support Annex 1 alignment, and deliver labor savings of up to 90%.

Digital Process Twin Cuts J&J Production Time And Costs

Virtual process modeling is helping to cut production time, reduce solvent use, and improve sustainability. See how digital twins enable faster scale‑up decisions and more efficient manufacturing.

Applying ncAA Incorporation To CRM197 Vaccine Carrier Protein Engineering

Achieving precise, site-specific conjugation on vaccine carrier proteins requires careful structural analysis to avoid disrupting critical functional regions and immune response pathways.

Understanding The Amazing Benefits Of Organoids

In this discussion, Dr. Alexis Santana explains what organoids are, how they are developed and applied, and why they are becoming a transformative tool in modern drug development.

Bridging Discovery And CMC With Rapid Pools

Delve into how early stable CHO expression data reveals manufacturability issues in complex antibodies that transient screening misses, with case studies showing how this changes lead selection.

Innovations In Peptide Manufacturing

The peptide manufacturing industry is evolving to meet the demands of efficiency, scalability, and sustainability. Read about the latest innovations that are addressing these challenges.

Add mRNA Capacity — Flexibly

Learn about a platform that addresses five critical pain points to help mRNA manufacturers flexibly scale while improving the digital maturity of their sites.

Engaging Early In Process Development To Bring mRNA Sequences To Life

Examine why template sequence characteristics are relevant for cGMP manufacturing of high-quality mRNA and consider insights on how to develop a scalable, robust, and economically viable process.

Soluble Versus Insoluble Expression In Microbial Fermentation

Expression of inclusion bodies has historically suffered a bad reputation in the industry. So, how do these two routes, soluble and insoluble, compare in terms of their advantages and challenges?

Find The Perfect Balance Between Yield And Desired Glycosylation

Achieving desired glycosylation for therapeutic proteins can be difficult. Observe innovative approaches to optimize this critical quality attribute.

The Spirit Of MISEV

MISEV guidelines help extracellular vesicle researchers design robust experiments through transparent reporting and rigorous characterization rather than rigid checklists.

Defined Media, Defined Results: Scaling E. coli From Bench To Fermenter

Understand the benefits of chemically defined media in E. coli systems, explore real-world plasmid DNA data, and learn practical strategies for scaling to robust manufacturing.

PROCESS ENGINEERING SOLUTIONS

Leak-Free Tubing Retainers Like Never Before - Nordson MEDICAL

XYZ Nanopositioning System - Mad City Labs, Inc.

Complete Solutions For Every Step Of Pharmaceutical Development - Cytiva

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