04.13.26 -- Immobilized Enzymes Promise Alternative To Cyanogen Bromide's Toxicity

Learn five essential best practices to maintain a sterile incubator shaker environment, from routine cleaning and humidity control to advanced HEPA filtration for reliable results.

Discover how transposon technology is being reimagined as a genetic engineering tool to create high-performing CHO cell lines for biotherapeutic production with enhanced metabolic and glycan profiles.

Examine how to effectively use small-scale perfusion-mimic systems to identify optimal cell culture media and significantly increase volumetric productivity for large-scale biomanufacturing.

Explore a streamlined approach to transient AAV production, including yield improvements across serotypes, key transfection parameters, and practical guidance for scaling processes.

Transitioning to closed systems enables the 100-fold expansion of engineered cells. Achieve high yields and maintain anti-cancer potency while reducing contamination risks and labor.

Lipid nanoparticles enable precise, non-viral gene editing in T cells to achieve high HDR efficiency and viability in scalable workflows. See how this approach overcomes viral vector limitations.

Perfusion-based upstream production offers up to 24% lower cost and significantly higher productivity than fed-batch, enabling faster timelines, better facility utilization, and improved quality.

Oxygen heterogeneity, caused by pressure variations and other factors in large-scale bioreactors, can significantly impact cell growth and product yield.

Reduce the time and risks involved in maintaining a traditional bioreactor with this single-use solution for biopharmaceutical manufacturers.