01.26.24 -- How Can Digital Twins Get Us Closer To Pharma 4.0?

In response to the growing demand for monoclonal antibodies, researchers are looking at different areas of the downstream process where they can improve efficiency and scalability.

Discover how to construct an agreement between partners that favors fluid communication and alignment of business objectives — crucial for a fruitful CDMO relationship to diminish risk for both.

Build an understanding of operational excellence by looking at what vertical startups are and why operational readiness is necessary for them to exist.

Investigate how using a peak expression cell culture medium in the right bioreactor can promote recombinant protein production and improve the performance of a scalable AAV process.

In this chapter of The Aqueous Cleaning Handbook, we explore the key definitions of aqueous cleaner ingredients, the types of aqueous cleaners, and the application of isoelectric points to cleaning.

Review the advantages and limitations of transcriptional assays versus reporter gene assays and how the transcriptional assay compares to ddPCR and flow cytometry for analysis of CGTs.

Thorough consideration of cleaning/disinfection during facility design eases maintenance across the facility life cycle, optimizes workspace utility, and contributes to efficient facility operation.

Learn the details and result of an autosampler and bioreactor pairing that was used for the sampling of eight parallel fermentation runs and for storing the samples in a cooling stack.

Explore the benefits of working with a CDMO that has extensive plasmid experience and integrated project teams across the production process.

By founding their latest venture, Abpro, Ian and Eugene Chan are using their synergistic skillsets in business and medicine to rapidly generate antibodies that treat cancer and autoimmune diseases.