Newsletter | February 2, 2026

02.02.26 -- Here's A Thought: What If Gene Editing Didn't Use Bacterial Enzymes?

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Join Bioprocess Online Chief Editor Tyler Menichiello on February 11, at 11 a.m. Eastern, for an interactive panel discussion exploring how upstream and downstream development teams can work together to reduce risk, accelerate process scaling, and support smoother downstream tech transfer. Register for free thanks to support from Ecolab.

FOCUS ON UPSTREAM MANUFACTURING

Here's A Thought: What If Gene Editing Didn't Use Bacterial Enzymes?

Citing the dismally few wins for CRISPR/Cas9 and other gene editing systems, one scientist proposes delivering zinc finger DNA-binding peptides using AAV6 vectors.

Why Cell Washing Is The Hidden Bottleneck In Gene-Edited Cell Therapy

Scaling up life-saving gene-edited cell therapies means tackling production inefficiencies. Overcoming the time-consuming and risky cell washing step is crucial for clinical and commercial success.

A Deep Dive Into QuickStart Media

Learn how this game-changing platform simplifies the complex process of custom media design, empowering researchers to expedite their development and achieve optimal results.

Automated Sampling Of A Four Vessel Parallel CHO Cell Culture

Examine how automated sampling for parallel bioreactors enables continuous, sterile sample collection from CHO cell cultures, maintaining cell density with reduced manual intervention.

Making MSCs GMP: A Compliant Workflow

Generate GMP-compliant mesenchymal stem cells (MSCs) at scale with a closed, automated workflow. Learn how to optimize MSC harvest yields and ensure trilineage differentiation.

Beyond Glycan Control: The IVGE Advantage In Key Biopharma Applications

In Vitro Glycoengineering (IVGE) precisely controls glycosylation to optimize biopharma workflows, serving as a critical platform for advancing key therapeutic areas in today's industry.

Efficient Mammalian Cell Engineering For Difficult Protein Expression

By leveraging cells equipped with an existing TARGATT™ landing pad, we demonstrate how inducible expression can be efficiently achieved within just 4-6 weeks after donor plasmid creation.

Maintain Sterility And Ease In CGT Development, Including Cryopreservation

Sterile connectors streamline cell and gene therapy processes while maintaining sterility. By withstanding extreme temperatures and cryoprotectants, they can ensure product viability during cryopreservation.

UPSTREAM MANUFACTURING SOLUTIONS

Accelerating CHO Bulk Harvest Testing Requires Rapid Methods - MilliporeSigma

CRISPR From Research To Therapy - Lonza

Enable Your Perfusion Process And Maximize Productivity - FUJIFILM Biosciences

Compact Design, Customizable Stainless-Steel Bioreactor - INFORS HT

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