Evaluation & Application Of Amsphere A3 In Downstream Purification Processes

Multiple Protein A resins are available for use in the purification of Fc-containing biologics. IKBI Biopharma Inc. has developed a rapid and streamlined workflow for comparing capacity and product quality from different ProA resin candidates as part of the larger downstream purification process development effort. This workflow has been utilized to compare Amsphere A3 resin to other high-performance Protein A resins available on the market since 2016.

This presentation will cover the results of these comparisons in terms of ProA resin capacity and eluate product quality as well as later development data comparing viral clearance results for these different affinity resins.