Amsphere™ A3 Brochure

• Alkali Resistant and Optimized Ligand for High Capacity
• Surface Modified Base Bead for High Purity
• Semi-rigid Bead for High Productivity

True polymer innovation that bridges amorphous materials and agarose for advanced protein separation.

Protein A chromatography is widely used as the affinity capture step of both mAbs and Fc-fusion proteins because of its high degree of selectivity. Variations in elution behavior of the protein A capture step requires more process development work and could have an impact on the polishing step in the downstream process. Thus minimizing the variation in elution pH between different molecules for example, makes it easier to platform the capture process.