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| Evaluation of a New Multimodal Resin for Emerging Biotherapeutics | As biotherapeutics become more complex, purification scientists need flexibility for process optimization. This 15-minute on-demand webcast, Merck & Co., Inc., presents how Bio-Rad’s Nuvia™ wPrime 2A Media, a weak anion exchange and hydrophobic interaction chromatography (AEX-HIC) mixed-mode resin, provides a broad design space and improved yields while reducing aggregates and HCPs in comparison to existing monoclonal and bispecific antibody workflows. Watch now and request a sample. |
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FOCUS ON DOWNSTREAM MANUFACTURING |
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| How To Define, Monitor, And Hit Critical Endpoints | Webinar | Repligen | Improve UF/DF repeatability by defining clear concentration and diafiltration endpoints, matching them with appropriate measurements, and applying real-time in-line analytics to reduce variability. |
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| Process Intensification Of Protein A For mAb Purification | Article | By Sayali Kulkarni, Anupama Kante, Jericho Coquilla, et al., W.L. Gore & Associates | See how membrane and multi-column chromatography compare with traditional Protein A capture in productivity, cost, scalability, and performance, including results from pilot-scale membrane testing. |
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| Simplifying Downstream Processing For Complex Biologics | Q&A | By Kenneth Holbourn, FUJIFILM Biotechnologies | Uncover how integrated approaches and process simplification can reduce bottlenecks, improve consistency, and support high-quality manufacturing outcomes across increasingly challenging pipelines. |
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DOWNSTREAM MANUFACTURING SOLUTIONS |
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By Robert Dream | The field has evolved considerably in antibody–drug conjugate (ADC) science. In this first article of a two-part series, let's discuss how to engineer better ADCs, covering MoA, conjugation chemistry, and more. | |
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| Neoantigen-Based Personalized Cancer Vaccine | Poster | By Jay Paquette, Mehar Gayatri Namala, Leanna Yee, et al., Cytiva | Personalized cancer vaccines are advancing quickly, but effective delivery remains a major hurdle. Learn how mRNA and lipid nanoparticle design influence targeting, endosomal escape, and repeat dosing. |
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| Automated Fill And Finish For Cell Therapy | Application Note | CellBri | Automated fill-finish systems protect sensitive cell therapies using low-shear handling to maintain dose uniformity, cell viability, and process consistency across every batch. |
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