10.27.25 -- CRISPR And iPSC Disease Modeling And Drug Screening

Single-use tubular bowl centrifuges are standing out to cell therapy developers for their ability enable the optimal balance between high separation efficiency, high productivity, and low shear.

Learn about a method for generating human iPSC-derived cerebellar organoids that allows for the reproducible and large-scale production that recapitulate key features of cerebellar development.

Discover the potential of T1 cell-derived nanoparticles (CDNPs) to accelerate T-cell activation. See how CDNPs’ unique mechanism of mimicking physiological immune stimulation positions them for broad use.

Ensuring media identity and consistency is vital in biologics manufacturing. Find out why quantifying cell culture media components before batch release helps overcome formulation complexity.

Uncover how TFDF-based perfusion technology boosts lentiviral vector production by over 10-fold, slashes costs, and accelerates the commercialization of CAR-T and other advanced cell therapies.

This technical guide provides information on the most common methods of gene delivery and compares them to Nucleofection. Delve into their advantages, disadvantages, and ideal applications.

Examine how a chemically defined viral feed can boost AAV titers by up to 8-fold, supporting multiple serotypes and both suspension and adherent HEK293 cell lines, simplifying scalability.

By following the five steps of a specialized protocol, exceptional yields and stable cell lines can be achieved in CHO cells using antibiotic selection.

Gain insight into how engineered exosomes, displaying tumor-homing peptides, offer a promising tool for targeted cytotoxic drug delivery, produced efficiently with a bioreactor for critical research.

Read about a scalable transfection method for suspension CHO cells grown in flasks on an orbital shaker platform, resulting in improved protein yields while maintaining cell viability.