Newsletter | March 31, 2025

03.31.25 -- Cell Line Selection In Novel Protein Therapeutic Development

SPONSOR

Webinar: Navigating Global Regulatory Landscapes in an Evolving Biopharma Industry

This webinar offers insights into managing raw material changes and navigating regulatory challenges in the biopharma industry. Experts will discuss collaboration between suppliers and users, risk management, change management, and adapting to evolving regulations. Key objectives include mastering regulatory guidance, implementing effective change management, and understanding market trends. Join us to explore best practices and remain compliant throughout drug development. Click here to learn more.

FOCUS ON UPSTREAM MANUFACTURING

Cell Line Selection In Novel Protein Therapeutic Development

By Bioprocess Online Live

During a Bioprocess Online Live event about early bioprocessing considerations, Lena Tholen, Ph.D., and Meinhard Hasslacher, Ph.D., weigh in on important cell line selection considerations.

Simplified LV And AAV Clarification With Intensified Virus Production

Application Note | Repligen

Learn how Tangential Flow Depth Filtration (TFDF) enhances viral vector production, streamlining the clarification process and increasing efficiency and yield for LV and AAV manufacturing.

Enabling Cell Line Tech Transfer For mAb Platform Manufacturing

Article | By Steve Loftus, FUJIFILM Diosynth Biotechnologies

Technology transfer, the transmission of bioprocess knowledge, skills and technology, is a crucial mechanism for ensuring adequate and timely access to innovative medicines.

Systematic Approach to Enhancing iPSC Expansion

Webinar | Eppendorf SE

Stirred-tank bioreactors can optimize hiPSC expansion. Discover a systematic optimization strategy that significantly boosts cell density while preserving crucial stem cell characteristics.

Bench To Bedside: Trends In Regenerative Medicine

White Paper | Corning Life Sciences

Discover the promising capabilities of regenerative medicine. Learn about four advanced techniques that can restore damaged tissue and offer hope to patients with severe conditions.

Choose The Right Bioreactor Size For Your Cell Expansion

Application Note | Terumo BCT

Compare expansion parameters when adherent cells are cultured on the small and standard bioreactors using a hollow-fiber bioreactor platform.

Shaping Biotherapeutics Development Programs Around Different CMC Paths

Article | By Nathalie Knabe, Lonza

As protein engineering and manufacturing technologies evolve, there's a need for flexible, customized strategies to accelerate drug development and approval of biotherapeutics.

Unleashing The Power Of Perfusion In Intensified Processes

Webinar | MilliporeSigma

Explore the advantages of implementing a perfusion-specific CLD process to produce more productive clones as well as an integrated solution for intensified processing.

SPONSOR

The debate rages on. While the automation that enables continuous processing gets a lot of hype, there are plenty of dyed-in-the-wool biopharma pros who contend that process optimization and intensification yield comparable benefits, without requiring the capital-intensive process overhaul that continuous demands. Join Bioprocess Online Live for a virtual deep dive into the scalability, sustainability, and capital implications of the continuous-versus-optimized debate. Registration is free thanks to the support of Cytiva.

UPSTREAM MANUFACTURING SOLUTIONS

•

TransIT-AAViator Transfection System - Mirus Bio

•

Banking The Intensified Seed Train - Single Use Support

Connect With Bioprocess Online: